Results 121 to 130 of about 16,736,389 (319)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Curl-conforming hierarchical vector bases for triangles and tetrahedra [PDF]

, 2011
A new family of hierarchical vector bases is proposed for triangles and tetrahedra. These functions span the curl-conforming reduced-gradient spaces of Nédélec.
Peterson A. F., Graglia, Roberto, Andriulli, Francesco, Andriulli, F.P., Andrew F. Peterson, Peterson, Andrew, Roberto D. Graglia, Andriulli F. P., Peterson, A.F., Francesco P. Andriulli   +9 more
core   +1 more source

Susceptibility of Amblyomma sculptum, Vector of Rickettsia rickettsii, Ticks from a National Park and an Experimental Farm to Different Synthetic Acaricides. [PDF]

Pathogens, 2023
Cardoso ERN, Carvalho SF, Dias SA, Santos RA, Tavares MA, Neves LC, Paula WVF, Pádua GT, de Lima NJ, Paludo RLDR, Silva IS, Bittencourt RBM, Dos Santos GC, Nascimento FGJ, de Paula LGF, Dantas-Torres F, Monteiro CMO, Krawczak FDS.   +17 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Experiences In Comprehensive Vector Control In Indonesia [PDF]

, 2012
The vector control program has been implemented in Indonesia for many years, however, vector-borne diseases are presently still a problem in Indonesia. Past activities for vector control implemented indoor residual spraying and larviciding only.
Nalim, Sustriayu; VECTOR CONTROL RESEARCH STATION, HEALTH ECOLOGY RESEARCH CENTER
core   +1 more source

Risk Factors for QRS-Fragmentation in Patients with STEMI Undergoing PCI

Medicina
Background and Objectives: Despite modern therapy algorithms, ST-elevation myocardial infarction (STEMI) substantially contributes to cardiovascular morbidity and mortality worldwide.
Florian Tinhofer, Rosana Rakhimova, Elena A. Badykova, Lukas Fiedler, Dilvin Semo, Christoph C. Kaufmann, Irina A. Lakman, Eduard F. Agletdinov, Dimitry M. Grishaev, Ksenia A. Cheremisina, Anastasia V. Baraboshkina, Lukas J. Motloch, Rudin Pistulli, Naufal S. Zagidullin   +13 more
doaj   +1 more source

Measurement of Magnetic and Magnetostrictive Characteristics of Transformer Core Based on Triaxial Strain Gauge and B-H Vector Sensor. [PDF]

Sensors (Basel), 2023
Wang Z, Fan Z, Li X, Xu K, Yu R.
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Vector perturbation technique [PDF]

, 2010
La “vector perturbation technique” è una tecnica di codifica che permette di avvicinarsi alla capacità teorica del canale in un sistema MIMO. Questa tecnica va a operare sul vettore dati da trasmettere e si articola in quattro punti fondamentali: Channel
Vianello , Alessandro
core  

Different viral genes modulate virulence in model mammal hosts and Culex pipiens vector competence in Mediterranean basin lineage 1 West Nile virus strains. [PDF]

Front Microbiol, 2023
Fiacre L, Nougairède A, Migné C, Bayet M, Cochin M, Dumarest M, Helle T, Exbrayat A, Pagès N, Vitour D, Richardson JP, Failloux AB, Vazeille M, Albina E, Lecollinet S, Gonzalez G.   +15 more
europepmc   +1 more source