Results 1 to 10 of about 52,745 (219)

The Histone Deacetylase Inhibitor I13 Induces Differentiation of M2, M3 and M5 Subtypes of Acute Myeloid Leukemia Cells and Leukemic Stem-Like Cells

open access: yesFrontiers in Oncology, 2022
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by reduced differentiation of myeloid cells and uncontrolled cell proliferation.
Liuya Wei, Zhe-Sheng Chen, Zhenbo Hu
exaly   +3 more sources

I13 overrides resistance mediated by the T315I mutation in chronic myeloid leukemia by direct BCR-ABL inhibition

open access: yesFrontiers in Pharmacology, 2023
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm caused by a BCR-ABL fusion gene. Imatinib has significantly improved the treatment of CML as a first-generation tyrosine kinase inhibitor (TKIs). The T315I mutant form of BCR-ABL is the most
Zhe-Sheng Chen
exaly   +3 more sources

Coherent imaging at the Diamond beamline I13

open access: yesPhysica Status Solidi (A) Applications and Materials Science, 2011
AbstractThe Diamond beamline I13 for imaging and coherence applications is dedicated to hard X‐ray imaging on the micro and nano‐lengthscale. Two independent stations will be operated in a separate building at a distance of 250 m from the source. The imaging branch will perform in‐line phase contrast imaging and tomography over a large field of view in
Christoph Rau   +3 more
exaly   +2 more sources

Differences by sex and type of hypertension in mortality from hypertensive diseases between 1997 and 2020, and predictions for 2035 in Latin American and Caribbean countries. [PDF]

open access: yesPLoS ONE
BackgroundHypertension is the most prevalent cardiovascular condition and a leading contributor to premature mortality in Latin America and the Caribbean (LAC).
J Smith Torres-Roman   +11 more
doaj   +2 more sources

Hierarchical Generalized Linear Models: The R Package HGLMMM [PDF]

open access: yesJournal of Statistical Software, 2011
The R package HGLMMM has been developed to fit generalized linear models with random effects using the h-likelihood approach. The response variable is allowed to follow a binomial, Poisson, Gaussian or gamma distribution.
Marek Molas, Emmanuel Lesaffre
doaj   +1 more source

A Bayesian Analysis of Unobserved Component Models Using Ox [PDF]

open access: yesJournal of Statistical Software, 2011
This article details a Bayesian analysis of the Nile river flow data, using a similar state space model as other articles in this volume. For this data set, Metropolis-Hastings and Gibbs sampling algorithms are implemented in the programming language Ox.
Charles S. Bos
doaj   +1 more source

An Excel Add-In for Statistical Process Control Charts [PDF]

open access: yesJournal of Statistical Software, 2009
t shifts in processes in, for example, manufacturing. Among these are control charts".Control charts and other SPC techniques have been in use since at least the 1950s, and,because they are comparatively unsophisticated, are often used by management or ...
Samuel E. Buttrey
doaj   +1 more source

Numerical Integration in S-PLUS or R: A Survey [PDF]

open access: yesJournal of Statistical Software, 2003
This paper reviews current quadrature methods for approximate calculation of integrals within S-Plus or R. Starting with the general framework, Gaussian quadrature will be discussed first, followed by adaptive rules and Monte Carlo methods.
Diego Kuonen
doaj   +1 more source

Discovery of indole-3-butyric acid derivatives as potent histone deacetylase inhibitors

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
In discovery of HDAC inhibitors (HDACIs) with improved anticancer potency, structural modification was performed on the previous derived indole-3-butyric acid derivative.
Yiming Chen   +4 more
doaj   +1 more source

Indian Government Schemes Based Analysis on Women Empowerment In Financial Inclusion

open access: yesStudia Universitatis Vasile Goldis Arad, Seria Stiinte Economice, 2023
In general Women belonging to villages tend to spend the maximum of their time in household activities without any hesitation. In return, they don’t receive any merits or credits from the family and society.
Singh Tanu, Pande Sarveshwar
doaj   +1 more source

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