Results 41 to 50 of about 55,432 (266)

3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species

open access: yesAdvanced Science, EarlyView.
ABSTRACT Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...
Yueyuan Liu   +11 more
wiley   +1 more source

Schlouder: A broker for IaaS clouds [PDF]

open access: yesFuture Generation Computer Systems, 2017
In the field of cloud computing, Infrastructure as a Service (IaaS) provides virtualized on-demand computing resources on a pay-per-use model. IaaS Cloud differ from traditional mutualized infrastructures in that the resources can be dynamically claimed and released, and the real hardware infrastructure is unknown to its users.
Etienne Michon   +4 more
openaire   +1 more source

Efficient Monte Carlo simulation of streamer discharges with deep-learning denoising models

open access: yesMachine Learning: Science and Technology
Electric breakdown in non-conducting gases is a complex process that in its first stages is characterized by filamentary discharges called streamers. Streamer dynamics are inherently nonlinear and span broad temporal and spatial scales, making numerical ...
F M Bayo-Muñoz   +2 more
doaj   +1 more source

The relationship of floral differentiation and ABP gene expression on cucumber cotyledon cultures(黄瓜子叶培养物的花芽分化和ABP基因表达间的关系)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2000
黄瓜子叶培养物在pH7.0的培养基上培养1d而后转入正常培养基(pH5.8),能显著提高黄瓜子叶培养物的成花率。对pH7.0处理1d的子叶柄中游离IAA含量水平的检测表明:pH7.0处理降低了子叶柄中IAA的含量水平;ABP基因的表达情况均高于对照组。因此pH7.0处理对黄瓜子叶柄同时具有促进ABP基因表达和降低游离IAA含量水平的作用。
DUQin(杜勤)   +3 more
doaj   +1 more source

Clinical Utility and Outcome Prediction of Early ZnT8-IgG Testing and Titer in Type 1 Diabetes

open access: yesJCRPE, 2023
INTRODUCTION: Type 1 diabetes autoantibodies are directed against multiple antigens including: glutamic acid decarboxylase, protein tyrosine phosphatase-like islet antigen 2 (IA2), insulin (IAA), and Zinc transporter 8 protein (ZnT8).
Amanda Dahl   +3 more
doaj   +1 more source

Covalent Inhibition of SHMT2 by Gambogic Acid Induces Ferroptosis Through Mitochondrial Collapse in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
In this study, chemoproteomics combined with genetic and functional analyses was integrated to identify SHMT2 as a covalent and functional target of gambogic acid (GA) in triple‐negative breast cancer (TNBC). Further validation demonstrated that GA selectively modifies the Cys241 site of SHMT2, triggering mitochondrial dysfunction, activating the Nrf2 ...
Tong Yang   +15 more
wiley   +1 more source

Induction of Apple Cucumber (Cucumis melo) Buds Development by Combination of Kinetin and IAA In B5 (Gamborg) Medium

open access: yesJurnal Mangifera Edu, 2021
Research on indirect organogenesis of apple cucumber (Cucumis sp.) Was conducted from June until August 2020. The aim of the study is to get the best results from IAA and Kinetin concentrations on the growth of buds organogenesis to apple cucumber plants
Pritha Nour Mustikawaty   +1 more
doaj   +1 more source

Quantitative Mass Spectrometry‐Based Biodistribution of Monoclonal Antibodies: An Alternative to Radio‐Biodistribution

open access: yesAdvanced Science, EarlyView.
Monoclonal antibodies are powerful anticancer therapeutics targeting tumor‐associated antigens. Mass spectrometry enables precise and accurate quantification of mAbs in tumor plasma and healthy organs. Unlike ligand binding assay and radioactivity, mass spectrometry does not suffer from matrix effects and labelling artefacts while facilitating method ...
Domenico Ravazza   +9 more
wiley   +1 more source

Investigating in vitro culture of Abu Jahl watermelon plant Citrullus colocynthis (L.) Schrad [PDF]

open access: yesفیزیولوژی محیطی گیاهی, 2007
In this research, the determination of the best cultivation environment for stem organogenesis and the selection of the most suitable cultivar from Abu Jahl watermelon seeds have been studied.
s Qara Matrosyan, m Ghorbanli
doaj  

Orthogonal Ionic Liquid‐Based Extraction Strategy Enables Amyloid‐Specific Profiling of Aggregate Proteome

open access: yesAdvanced Science, EarlyView.
An orthogonal ionic‐liquid extraction (Orth‐iEA) enables selective isolation of amyloid fibrils. TMGBF4 disrupts hydrogen‐bonded β‐sheet networks to solubilize amyloid aggregates, whereas C12ImCl interacts with hydrophobic regions of non‐amyloid proteins.
Shiying Zheng   +10 more
wiley   +1 more source

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