Results 61 to 70 of about 55,645 (264)

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

open access: yesAdvanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li   +15 more
wiley   +1 more source

SIZ1‐Mediated SUMOylation of LBD29 Recruits ARF7 to Fine‐Tune Auxin Signaling in Lateral Root Development

open access: yesAdvanced Science, EarlyView.
Our findings establish SUMOylation as a key post‐translational control layer in auxin signaling. We show that SIZ1‐mediated SUMOylation of LBD29 promotes its association with ARF7, stabilizing a transcriptional hub that governs lateral root development.
Jiaxuan Sui   +7 more
wiley   +1 more source

Perfusion strategy and surgical repair of Type A interrupted aortic arch and Type 1 aortopulmonary window: a case report

open access: yesThe Journal of ExtraCorporeal Technology
Overview: Interrupted aortic arch in combination with an aortopulmonary window is an uncommon congenital cardiovascular defect. The anatomic separation between the aortic arch and descending aorta, combined with the communication between the ascending ...
Leigh Paula, Harman Ed, Husain S. Adil
doaj   +1 more source

Promotion of Growth and Fruits Quality Parameters of Tomato Plant by Bio-Fertilizers (Trichoderma Harzianum and EM1) and IAA [PDF]

open access: yesTikrit Journal for Agricultural Sciences
The present study was carried out in Hamah province, Syria, during the period from (2021-2022), to study the effect of treatment with Trichoderma harzianum bio-fertilizer (at a concentrations of 105, 106, 107 spores/ml) and EM1 bio-fertilizer (at a ...
Mais Naoof, Roula Bayerli
doaj   +1 more source

A Universal Protein Ladder for Standardization of Diverse FRET Assays

open access: yesAdvanced Science, EarlyView.
Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith   +5 more
wiley   +1 more source

IaaS Service Selection Revisited

open access: yes, 2018
Cloud computing is a paradigm that has revolutionized the way service-based applications are developed and provisioned due to the main benefits that it introduces, including more flexible pricing and resource management. The most widely used kind of cloud service is the Infrastructure-as-a-Service (IaaS) one.
Kyriakos Kritikos, Geir Horn
openaire   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

open access: yesAdvanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries   +25 more
wiley   +1 more source

THE CONTENT OF PLANT HORMONES IN CALLUS TISSUE DURING THE INDUCTION OF SOMATIC EMBRYOGENESIS IN EMBRYOS OF NORWAY SPRUCE (PICEA ABIES [L.] KARST.)

open access: yesTransactions of the Karelian Research Centre of the Russian Academy of Sciences, 2016
Somatic embryogenesis was induced in embryos of Picea abies by adding 2,4-D and BAP to the culture medium. The content of IAA, ABA, zeatin-ribosid and 2ip was determined at various stages of callus tissue formation using ELISA. The process of embryogenic
Konstantin Hmara
doaj   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

open access: yesAdvanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma   +14 more
wiley   +1 more source

Qualitative Assessment of Beneficial Microorganisms

open access: yesProceedings, 2019
Modern agriculture needs various plant growth stimulant products.
Iuliana RĂUT   +6 more
doaj   +1 more source

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