Results 101 to 110 of about 35,093 (269)

Proteome‐Wide Analysis of Palmitoylated Proteins in Macrophages Reveals Novel Insights Into Early Immune Signaling

PROTEOMICS, EarlyView.
ABSTRACT Protein S‐palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains incompletely understood.
Hyojung Kim, Jiraphorn Issara‐Amphorn, Sung Hwan Yoon, Anirban Banerjee, Aleksandra Nita‐Lazar   +4 more
wiley   +1 more source

Single‐Cell Nanodroplet Processing Proteomics Pipeline for Analysis of Human‐Derived Microglia

PROTEOMICS, EarlyView.
ABSTRACT Single‐cell omics tools provide unique insights into heterogeneous cell populations and their responses to stimuli. For example, single‐cell RNA sequencing has identified several transcriptionally distinct populations of microglia, which are resident immune cells of the central nervous system (CNS) that are responsive to CNS injury, infection,
Ashley N. Ives, James M. Fulcher, Alex R. Bautista, Reta Birhanu Kitata, Sarah M. Williams, David A. Bennett, Philip L. De Jager, Vladislav A. Petyuk   +7 more
wiley   +1 more source

Anthrax in Humans, Animals, and the Environment and the One Health Strategies for Anthrax Control

Pathogens
Anthrax is a notorious disease of public health importance caused by Bacillus anthracis. The causative agent can also be used as a biological weapon.
Deepak Subedi, Saurav Pantha, Sumit Jyoti, Bickal Gautam, Krishna Kaphle, Rakesh Kumar Yadav, Shristi Ghimire, Santosh Dhakal   +7 more
doaj   +1 more source

Mass Spectrometry Proteomics of the Nanoparticle Corona Is Highly Dependent on Sample Preparation Protocol

PROTEOMICS, EarlyView.
ABSTRACT It is widely established that the layers of proteins bound to the surface of nanoparticles (NPs), also known as the protein corona, critically influence their behavior in biological environments. Despite numerous proteomics studies performed in different NP‐corona systems, the impact of proteomic sample preparation methods on corona profiling ...
Asia Saorin, Alberto Martinez‐Serra, Michael Henry, Paula Meleady, Marco P. Monopoli   +4 more
wiley   +1 more source

Genotype × environment interaction and selection parameters for high yielding wheat genotypes under irrigated and heat stress environment

Journal of Sustainable Agriculture and Environment
Introduction Wheat is a significant contributor to the food and nutritional security of the world. Due to climatic constraints and heat stress condition, the potentiality of wheat to eradicate existing hunger and malnutrition has been severely limited ...
Radhakrishna Bhandari, Mukti R. Poudel
doaj   +1 more source

Comparison of In‐Gel and SP3 Based Sample Preparation Protocols for LC‐MS/MS Based Proteomics

PROTEOMICS, EarlyView.
ABSTRACT Sensitivity, robustness, and reproducibility of sample preparation are main determinants of data quality in bottom‐up mass spectrometry‐based proteomics. To this end, in‐gel protein clean‐up and digestion has been used for decades and is characterized by its robustness and compatibility with harsh lysis conditions.
Luisa Schwarzmüller, Dario Frey, Piotr Zadora, Martin Schneider, Stefan Wiemann, Dominic Helm   +5 more
wiley   +1 more source

SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies

PROTEOMICS, EarlyView.
ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà, Loredana Leggio, Greta Paternò, Elena Giusto, Laura Civiero, Vincenzo Cunsolo, Silvia Vivarelli, Antonella Di Francesco, Emanuele Alpi, Nunzio Iraci, Rosaria Saletti   +10 more
wiley   +1 more source

Research on Key Technology and Implementation of IaaS Resource Pool Disaster Recovery

Dianxin kexue, 2012
This paper describes the principle and application of key technologies of IaaS disaster recovery scene,explores how to build the disaster recovery system of the IaaS resource pool with these key technologies,and explores the basic principles should ...
Wensheng Yao, Jun Li, Heliang Ye, Ning Wan   +3 more
doaj   +2 more sources

Challenges for the comprehensive management of cloud services in a PaaS framework

, 2012
The 4CaaSt project aims at developing a PaaS framework that enables flexible definition, marketing, deployment and management of Cloud-based services and applications.
Andrikopoulos, Vasilios, Biro, József, García-Gómez, Sergio, Jiménez Gañán, Miguel, Junker, Frederic, Menychtas, Andreas, Momm, Christof, Strauch, Steve, Taher, Yehia   +8 more
core   +1 more source

Agroforestry and enhanced rock weathering: A dual strategy for sustainable cacao

PLANTS, PEOPLE, PLANET, EarlyView.
Cacao production is both economically vital and environmentally intensive, presenting a major sustainability challenge as a crop largely cultivated by smallholder farmers in climate‐vulnerable regions. This review synthesises evidence that integrating agroforestry with enhanced rock weathering (EW) may significantly reduce emissions from cacao ...
Isabella L. Steeley, Edson S. França, Dimitar Z. Epihov, Noah J. Planavsky, David J. Beerling   +4 more
wiley   +1 more source