Results 141 to 150 of about 34,906 (267)

A plant NLR receptor activates auxin signaling through Aux/IAAs-ARF19 and YUC8-TIR1/AFBs to promote callose-mediated antiviral defense. [PDF]

open access: yesSci Adv
Yang T   +18 more
europepmc   +1 more source

IAP Antagonists Selectively Eliminate Therapy‐Induced Senescent Cancer Cells via TNFα‐Independent Apoptosis

open access: yesCancer Science, EarlyView.
Upon chemotherapy, a subset of cancer cells enters a senescent state, referred to as TIS. When IAP antagonists are administered, TIS cells are selectively eliminated through TNFα‐independent apoptosis. TNFα secreted by TIS cancer cells may also act in a paracrine manner to enhance extrinsic apoptosis in neighboring non‐senescent cancer cells.
Hiroaki Ochiiwa   +7 more
wiley   +1 more source

A Critical Review of the 2025 RSHE Guidance and Alternative Approach Framed in Safe Uncertainty

open access: yesChildren &Society, EarlyView.
ABSTRACT This policy review critically examines the English government's 2025 statutory guidance on Relationships Education, Relationship and Sex Education and Health Education (RSHE), analysing its educational assumptions, strengths and limitations through the lens of safe uncertainty.
Emily Setty, Jonny Hunt
wiley   +1 more source

Impact of screening programmes for type 1 diabetes in youth: A systematic review and meta‐analysis

open access: yesDiabetic Medicine, EarlyView.
Abstract Aim To evaluate the impact of anti‐islet antibody (IAb) screening on the general population and first‐degree relatives (FDRs)/high‐risk individuals and evidence‐based follow‐up modalities. Methods We performed this review through systematic searches of PubMed, EMBASE, Cochrane Library, Web of Science, ClinicalTrials.gov and International ...
Roberto Franceschi   +24 more
wiley   +1 more source

The proteomic differences and expression of fatty acid‐binding protein 6 (FABP6) associated with gastrointestinal injury in horses with oral administration of a clinical dose of phenylbutazone

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Phenylbutazone (PBZ) can potentially induce gastrointestinal ulceration, and early detection of PBZ‐induced gastroenteropathy will be useful for the diagnosis, treatment, and prevention of PBZ toxicity. Objectives To identify putative proteins associated with equine gastric ulcer syndrome after clinical dose (4.4 mg/kg ...
Ruethaiwan Vinijkumthorn   +6 more
wiley   +1 more source

Aux/IAAs: specificity and redundancy. [PDF]

open access: yesPlant Signal Behav
Wen Q, Gong Q, Yu H, Yang P.
europepmc   +1 more source

L3 Regressive Transfer: A Study of Null Objects in the Basque and Spanish Grammars of Advanced L3 English Speakers

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT Regressive transfer has been a subject that has not been extensively researched in the field of third language acquisition. This study aims to examine the extent to which a highly advanced knowledge of a third language (L3) affects the first language (L1) and the second language (L2) of early bilinguals in light of the Differential Stability ...
Maddi Alkain Arizmendi   +2 more
wiley   +1 more source

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