Results 61 to 70 of about 3,629 (264)

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

Advanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma, Rui Wan, Yueyuan Zhong, Ziyang Cui, Xuan Zhang, Xiaoqiang He, Rong Wang, Lei Huang, Wan‐Yang Sun, Rong‐Rong He, Yang Zhou, Jianshuang Li, Li Shen, Shao‐Hua Wang, Tongzheng Liu   +14 more
wiley   +1 more source

Integrated effects of heat and drought stress on phenological, morphological, and biochemical traits of wheat for climate resilient breeding

Discover Plants
Wheat is a major cereal crop that feeds more than one-third of the global population. However, heat and drought stress pose a significant threat to wheat production and global food security.
Binod Panthi, Priyanka Kunwar
doaj   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

Advanced Science, EarlyView.
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang, Jinghan Zhu, Qian Xiao, Qichun Wei, Xiujing He, Ping Li, Kai Jiang, Yue Liu, Yeting Hu, Weiwei Yu, Chuansheng Guo, Sheng Chen, Jian Zhao, Siqi Dai, Jingsun Wei, Hang Yang, Tongtong Bu, Kefeng Ding, Haiyan Chen   +18 more
wiley   +1 more source

Heat stress and it’s tolerance in wheat

Cogent Food & Agriculture
The rise in world temperature has led to remarkable changes in global climate patterns, eventually devastating the crops. Climate change has led to the emergence of various abiotic factors which has decreased the crop’s productivity.
Sashi Bhusan Kumar Yadav, Suchi Bhatt
doaj   +1 more source

INTEGRATED NUTRIENT MANAGEMENT ON HYBRID MAIZE (ZEA MAYS L.) PRODUCTION IN LAMAHI DANG, NEPAL [PDF]

Big Data in Agriculture
The key to sustainable agricultural production and environmental protection is the prudent use of both organic and inorganic fertilizers. With these goals in mind, an experiment was carried out in the spring of 2021 in Lamahi municipality Dang district ...
Prabesh Pandit, Ramesh Khadka, Chiranjibi Puri   +2 more
doaj   +1 more source

The Mitogen‐Activated Protein Kinase GhNTF3 Modulates the Arbuscular Mycorrhizal Symbiosis‐Immunity Trade‐Off in Cotton by Regulating Salicylic Acid Biosynthesis

Advanced Science, EarlyView.
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia, Jingshang Wen, Jihang Li, Meina Feng, Yiming He, Ruojun Liu, Qian Liu, Junli Zhang, Kai Cheng, Xiangyu Zhang, Xiao Zhang   +10 more
wiley   +1 more source

Advances in Se Wide‐Bandgap Photovoltaics and TexSe1‐x SWIR Photodiodes

Advanced Science, EarlyView.
In this review, fundamental properties and current challenges in Se photovoltaics (PVs) for tandem and indoor PVs and TexSe1‐x alloys for short wave infrared photodiodes are discussed. A case is made for the practicality of elemental chalcogenide optoelectronics, and a pathway toward resolving the key challenges in these respective technologies is ...
Adam D. Alfieri, Deep Jariwala
wiley   +1 more source

Model-Driven Approach to Cloud-Portability Issue

Applied Sciences
This paper focuses on the portability of Cloud Computing (CC) services, specifically on the problems with the portability of Infrastructure as a Service (IaaS).
Marek Moravcik, Pavel Segec, Martin Kontsek, Lubica Zidekova   +3 more
doaj   +1 more source

CONCEPTUAL FRAMEWORK OF ANALYSIS OF INFORMATION SECURITY MODELS OF CLOUD SYSTEMS OF THE CLASS «INFRASTRUCTURE AS A SERVICE»

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019
A process based on the role approach for the synthesis of information security models of cloud computing systems based on applied system and threat models is described; the result is a security model, expressed, for example, in recommendations for ...
E. V. Olizarovich, A. I. Brazhuk
doaj   +1 more source