Results 71 to 80 of about 194,646 (276)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Evaluated Experimental Isobaric Analogue States from $T = 1/2$ to $T = 3$ and associated IMME coefficients

open access: yes, 2014
Isobaric multiplets can be used to provide reliable mass predictions through the Isobaric Multiplet Mass Equation (IMME). Isobaric analogue states (IAS) for isospin multiplets from $T=1/2$ to $T=3$ have been studied within the 2012 Atomic Mass Evaluation
Audi, G., MacCormick, M.
core   +5 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Documenting the Results of Audit of the Information Disclosed in the Notes to the Financial Reporting Compiled by International Standards

open access: yesСтатистика України, 2020
Financial reporting releases the information requiring disclosure in accordance with national or international accounting and reporting standards. This information is usually released in the notes to the financial reporting, intended for a broader range ...
О. Е. Lubenchenko
doaj   +1 more source

Symmetry Energy II: Isobaric Analog States

open access: yes, 2013
Using excitation energies to isobaric analog states (IAS) and charge invariance, we extract nuclear symmetry coefficients, from a mass formula, on a nucleus-by-nucleus basis.
Aboussir   +167 more
core   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Identification of the 37-kDa antigen in IDDM as a tyrosine phosphatase-like protein (phogrin) related to IA-2

open access: yesDiabetes, 1996
Antibodies to islet cell proteins detected as 37,000 and 40,000 Mr tryptic fragments (37- and 40-kDa antigens) are strongly associated with progression to IDDM. The 40-kDa antigen has recently been identified as the tyrosine phosphatase-like protein IA-2 (ICA512) whereas the 37-kDa antigen has been suggested to be a different protein that has ...
C. J. Hawkes   +3 more
openaire   +2 more sources

Charge-exchange scattering to the isobaric analog state at medium energies as a probe of the neutron skin

open access: yes, 2014
The charge-exchange (3He,t) scattering to the isobaric analog state (IAS) of the target can be considered as "elastic" scattering of 3He by the isovector term of the optical potential (OP) that flips the projectile isospin.
Khoa, Dao T.   +2 more
core   +1 more source

Frequency of financial reports [PDF]

open access: yes, 2013
Interim reports are summary statements that are usually prepared in semi-annual format in the UK. Until the EU’s Transparency Directive was put into practice in the UK in 2007, there was no legal necessity for companies to provide interim financial ...
Izadi Zadeh Darjezi, Javad   +1 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

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