Results 51 to 60 of about 390,111 (338)

Etelä-Karjalan IB-lukion imago, maine ja mielikuva [PDF]

, 2019
Tämän opinnäytetyön tarkoitus oli selvittää Etelä-Karjalan IB-lukion imago, maine ja mielikuvat Lappeenrannan koulujen opettajien, opinto-ohjaajien ja rehtoreiden keskuudessa.
Nikku, Juha
core  

SYNTHESIS OF HEAT-EXCHANGER NETWORKS WITH MINIMUM NUMBER OF UNITS FOR PINCHED PROBLEMS [PDF]

, 1992
An algorithmic-evolutionary synthesis procedure is studied for generating the maximum energy recovery (MER) and minimum number of units (MNU) networks with the goal of achieving the global optimum network under pinch points.
LEE, IB
core   +1 more source

The matrix reasoning item bank (MaRs-IB): novel, open-access abstract reasoning items for adolescents and adults

Royal Society Open Science, 2018
Existing non-verbal ability tests are typically protected by copyright, preventing them from being freely adapted or computerized. Working towards an open science framework, we provide 80 novel, open-access abstract reasoning items, an online ...
G. Chierchia, Delia Fuhrmann, L. Knoll, Blanca Piera Pi-Sunyer, A. Sakhardande, S. Blakemore   +5 more
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Characterization of P. aeruginosa isolates resistant to fluoroquinolones and/or carbapenems with regard to the minimum inhibitory concentration, bla_SPM, bla_VIM, qnrS, aac(6´)-Ib-cr and aac(6´)-Ib₇ genes, quinolone resistance determining region mutations and the PFGE patterns. [PDF]

, 2016
Characterization of P. aeruginosa isolates resistant to fluoroquinolones and/or carbapenems with regard to the minimum inhibitory concentration, blaSPM, blaVIM, qnrS, aac(6´)-Ib-cr and aac(6´)-Ib7 genes, quinolone resistance determining region mutations ...
Melina Lorraine Ferreira (2806411), Sabrina Royer (2806429), Ana Luiza Souza Faria (2806426), Paulo Pinto Gontijo-Filho (2806420), Iara Rossi Gonçalves (2806417), Jonny Yokosawa (2806408), Raquel Cristina Cavalcanti Dantas (2806414), Paola Amaral de Campos (2806432), Rosineide Marques Ribas (2806405), Bruna Fuga Araujo (2806402), Cristiane Silveira de Brito (2806423), Deivid William da Fonseca Batistão (2806399)   +11 more
core   +1 more source

Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer

Journal of Clinical Oncology, 2015
Purpose Sonic hedgehog (SHH), an activating ligand of smoothened (SMO), is overexpressed in > 70% of pancreatic cancers (PCs). We investigated the impact of vismodegib, an SHH antagonist, plus gemcitabine (GV) or gemcitabine plus placebo (GP) in a ...
D. Catenacci, M. Junttila, T. Karrison, N. Bahary, M. Horiba, S. Nattam, R. Marsh, J. Wallace, M. Kozloff, L. Rajdev, D. Cohen, J. Wade, B. Sleckman, H. Lenz, P. Stiff, Pankaj Kumar, Peng Xu, L. Henderson, N. Takebe, R. Salgia, Xi Wang, W. Stadler, F. D. de Sauvage, H. Kindler   +23 more
semanticscholar   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

sonemics I/Ib [PDF]

, 2012
sonemics I/Ib is an audiovisual work for live video and spatial sound made in 2012. It is a collaboration with film maker Kate Burton and is one of a series of live audiovisual pieces. It was performed at the SoundLab series at the City Halls, Glasgow in
Burton, K., Fells, N.
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source