Results 41 to 50 of about 390,111 (338)

Conformational effects of interaction of serum albumine with nanoparticles of carbon shungyte: epr spin-probe study

Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2018
Conformational effects of interaction between bovine and human serum albumin (SA) molecules and nanoparticles of shungite carbon (ShC) in aqueous dispersion have been studied in the temperature range 17 – 72 °С K using electron spin resonance (EPR) spin ...
Sergey Pavlovich Rozhkov, Andrey Sergeyevich Goryunov   +1 more
doaj   +1 more source

Phase Ib/II Study of Capmatinib (INC280) Plus Gefitinib After Failure of Epidermal Growth Factor Receptor (EGFR) Inhibitor Therapy in Patients With EGFR-Mutated, MET Factor-Dysregulated Non-Small-Cell Lung Cancer.

Journal of Clinical Oncology, 2018
PURPOSE MET dysregulation occurs in up to 26% of non-small-cell lung cancers (NSCLCs) after epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) treatment.
Yi-long Wu, Li Zhang, Dong-Wan Kim, Xiaoqing Liu, Dae-Ho Lee, J. Yang, M. Ahn, J. Vansteenkiste, W. Su, E. Felip, V. Chia, S. Glaser, P. Pultar, Sylvia Zhao, B. Peng, M. Akimov, D. Tan   +16 more
semanticscholar   +1 more source

Evolutionary Models for Type Ib/c Supernova Progenitors [PDF]

Publications Astronomical Society of Australia, 2015
SNe Ib/c mark the deaths of hydrogen-deficient massive stars. The evolutionary scenarios for SNe Ib/c progenitors involve many important physical processes including mass loss by winds and its metallicity dependence, stellar rotation, and binary ...
Sung-Chul Yoon
semanticscholar   +1 more source

UMA ANÁLISE DO PROCESSO DE ELABORAÇÃO DO PLANO MUNICIPAL DE EDUCAÇÃO DE RIO CLARO-SP

Educação: Teoria e Prática, 2017
O Plano Municipal de Educação (PME) é um importante instrumento que serve como guia de ação para o governo em oposição à imprevisibilidade. Ele deve expressar as diretrizes, as metas e os meios pelos quais o objetivos serão atingidos durante sua vigência,
Mariana Aparecida da SIlva, Maria Aparecida Segatto Muranaka   +1 more
doaj   +1 more source

Clade Ib: a new emerging threat in the Mpox outbreak

Frontiers in Pharmacology
Monkeypox, a zoonotic virus in the Orthopoxvirus genus, has drawn global attention for its impact on public health. In the current Mpox outbreak, a novel clade, Ib, has emerged as a significant and potentially fatal threat.
Shriyansh Srivastava, Laxmi, Khyati Sharma, S. Sridhar, S. Talath, J. Shareef, Rachana Mehta, Prakisini Satapathy, Ranjit Sah, C. Sirka, Tarik Aanniz   +10 more
semanticscholar   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Niche distribution and influence of environmental parameters in marine microbial communities: a systematic review [PDF]

PeerJ, 2015
Associations between microorganisms occur extensively throughout Earth’s oceans. Understanding how microbial communities are assembled and how the presence or absence of species is related to that of others are central goals of microbial ecology.
Felipe H. Coutinho, Pedro M. Meirelles, Ana Paula B. Moreira, Rodolfo P. Paranhos, Bas E. Dutilh, Fabiano L. Thompson   +5 more
doaj   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

TOWARD THE SYNTHESIS OF GLOBAL OPTIMUM HEAT-EXCHANGER NETWORKS UNDER MULTIPLE-PERIODS OF OPERATION [PDF]

, 1991
An algorithmic-evolutionary synthesis procedure is proposed for flexible heat exchanger networks (HEN) under multiple-periods of operation. After a feasible network is synthesized at each period, they are combined to form a feasible super network ...
LEE, IB
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source