Results 241 to 250 of about 669,213 (326)

A Protective Role of Hydrogen Sulfide Donor GYY4137 Through Activated Microglia-induced Anti-inflammatory Cytokines in the Spinal Cord of Diabetic Rats. [PDF]

Mol Neurobiol
Mousa AMA, AlDhaen M, Qabazard B, Renno WM, Yousif MHM.   +4 more
europepmc   +1 more source

GALNT3 Inhibits the Progression of Cerebral Ischemia–Reperfusion Injury by Stabilizing TREM2 via O‐GalNAc Glycosylation

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
The neuroprotective effect of GALNT3 against CIRI and the underlying mechanisms. GALNT3 directly interacts with and catalyzes the mucin‐type O‐GalNAcylation of TREM2 predominantly at serine 147, which enhances TREM2 protein stability. This GALNT3‐TREM2 axis suppresses the release of pro‐inflammatory cytokines, oxidative stress, and activation of M1 ...
Xinyi Fei, Jinghui Yang, Rui Zhang, Yu Zhang, Shan Yu   +4 more
wiley   +1 more source

β-Asarone Attenuates Neuroinflammation of Alzheimer's Disease by Activating Autophagy and Suppressing NLRP3 Inflammasome Assembly. [PDF]

CNS Neurosci Ther
Xu Z, Xu W, He J, Qian J, Wang H, Li C, Zhou X.   +6 more
europepmc   +1 more source

Evolutionary and Functional Characterization of an Auxin Methyltransferase (CsIAMT) in Cucumber Reveals Its Role in Stress Adaptation and Development

Ecology and Evolution, Volume 16, Issue 3, March 2026.
The plant SABATH methyltransferase family drives phenotypic diversity evolution through gene duplication and new functionalization. Among them, IAMT, as the most ancient member of this family, is widely present in various species. The study identified a potential auxin methyltransferase homologous to IAMT (CsIAMT) in cucumber, which can catalyze IAA ...
Xinjie Zhang, Yang Zhou, Mengxin Chen, Jingwen Li, Lisi Jiang, Ken Li, Lin Hao, Wei Fu   +7 more
wiley   +1 more source

Correction: Association between the 400-m walk test and sensor-based daily physical activity in frail and sarcopenic older adults. [PDF]

Eur Geriatr Med
Rogler J, Krumpoch S, Freiberger E, Lindemann U, Kob R.   +4 more
europepmc   +1 more source

Milk Fat Globule Membrane Supplementation Attenuates Cognitive Impairment in APP/PS1 Mice via Suppressing Neuroinflammation in a Gut Microbiota‐Mediated Serum Resolvin D1/Anandamide Manner

Food Frontiers, Volume 7, Issue 2, March 2026.
MFGM modulated gut microbiota accompanied by the increased serum RVD1 and AEA levels, which subsequently regulated the miRNA profile. This modulation alleviated neuroinflammation via suppressing the NLRP3 inflammasome signaling and microglial activation, thereby attenuating AD‐related cognitive impairment both in vivo and in vitro.
Han Gong, Qichen Yuan, Min Du, Xiaohan Liu, Xueying Mao   +4 more
wiley   +1 more source

Development of an efficient in vitro micropropagation and biochemical profiling of Salvia halophila, an endemic Turkish sage. [PDF]

BMC Plant Biol
Tanur Erkoyuncu M.
europepmc   +1 more source

Astragalus Polysaccharides Can Effectively Alleviate Cognitive Impairment in Mice With Alzheimer's Disease by Regulating the Gut Microbiota

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
This schematic diagram illustrates that Astragalus polysaccharides improve cognitive dysfunction in 3xTg AD mice by regulating the gut‐brain axis. APS ameliorates gut microbiota and enhances intestinal barrier function, thereby reducing systemic and central inflammation, inhibiting microglial overactivation, and alleviating Aβ deposition and Tau ...
Xilian Wang, Xinyun Ge, Xin Di, Zhiyan Zou, Dan Lei, Zihao Wang, Jiaqiang Hou, Yan Yang, Wanxue Zhang, Yuan Yin, Xinnuo Lei, Yu Long, Xuemin Jian, Xiaoan Li   +13 more
wiley   +1 more source

Global Comparison of Aqueous Geochemistry and Dissolved H2/CH4 in Continental Low Temperature Serpentinization–Influenced Environments

Hydrological Processes, Volume 40, Issue 3, March 2026.
Conceptual diagram of hydrological and geochemical processes within the Santa Elena Ophiolite, Costa Rica. It highlights watershed cross‐sections, soil genesis, hyperalkaline Type II waters (pH > 11.6) with calcite crust and trapped H2/CH4 gases, seepage into surface waters, storm‐impacted stream profiles, weathered vs.
Alexandra May, Ricardo Sánchez‐Murillo, Matthew O. Schrenk, Esteban Gazel, J. Maarten de Moor, Christian Birkel, Xiaoqiang Li, Danelle Carr, María Marta Chavarría   +8 more
wiley   +1 more source

Innate Immune Tolerance Regulates Microglia Response to Aβ Oligomers. [PDF]

J Neurochem
Valerio RR, Santos ÁR, Nóbrega AHL, Martins R, De Felice FG, Ferreira ST, Savino W, Bonomo A, Bernardi A, Frozza RL.   +9 more
europepmc   +1 more source