Results 251 to 260 of about 669,213 (326)

Neuronal Extracellular Vesicles Carrying APOE Downregulate Filament Actin Polymerization Signaling to Inhibit Synapse Formation in Alzheimer's Disease

Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
During AD progression, EVs derived from APP/PS1 neurons transport APOE into healthy neurons, potentially interacting with neuronal APOE receptors (LRP1, LDLR, VLDLR) to transduction the signaling. This signaling inhibits Rac1‐GTP activation and subsequently downregulates F‐actin polymerization through the Rac1‐N‐WASP‐Arp2/3 pathway.
Yang Yu, Zhixin Ma, Taixu Li, Wenjun Xiao, Zhigang Li   +4 more
wiley   +1 more source

Inhibition of galanin receptor 3 slows down retina degeneration in retinitis pigmentosa through modulation of inflammatory and oxidative stress response. [PDF]

Sci Rep
Azam M, Pashandi Z, Liu M, Jastrzebska B.   +3 more
europepmc   +1 more source

Impact of Incidental High Ocean Waves on Topographical Changes in the Adélie Penguin Colony at Edmonson Point on the Northern Victoria Land Coast, Antarctica

New Zealand Journal of Geology and Geophysics, Volume 69, Issue 1, March 2026.
Natural disaster‐driven environmental changes can have both direct and indirect effects on seabird breeding and nesting conditions. Edmonson Point, located on the Victoria Land coast in the Ross Sea, hosts around 3000 pairs of Adélie penguins (Pygoscelis adeliae), divided between coastal and hillside subcolonies differing in topography.
Youmin Kim, Younggeun Oh, Jong‐U. Kim, Jeong‐Hoon Kim   +3 more
wiley   +1 more source

The association between virus-induced spinal cord pathology and the genetic background of the host. [PDF]

J Neuropathol Exp Neurol
Lawley KS, Kang TW, Rech RR, Karmakar M, Carroll R, Perez Gomez AA, Amstalden K, Jones-Hall Y, Threadgill DW, Welsh CJ, Young CR, Brinkmeyer-Langford C.   +11 more
europepmc   +1 more source

An Optimised Protocol for Faba Bean (Vicia faba L.) Tissue Culture and Transformation

Legume Science, Volume 8, Issue 1, March 2026.
ABSTRACT Faba bean (Vicia faba L.) is an important legume that contributes to agricultural sustainability through nitrogen fixation and offers substantial nutritional benefits. Nonetheless, its genetic enhancement has been constrained by challenges associated with tissue culture and transformation.
Md Mamunur Rashid, Paridhi Paridhi, Sai Aravind Mandava, Marina Grölz, Babette Knoblauch, Stavros Tzigos, Rod J. Snowdon, Sruthy Maria Augustine   +7 more
wiley   +1 more source

The novel IDO-1 inhibitor 3-047 combined with icaritin ameliorates neuroinflammation and diabetes-associated cognitive dysfunction with suppression of TLR4/MyD88/NF-κB signaling. [PDF]

Front Immunol
Mo T, Zhuang X, Zhao W, Wang B, Wang Y, Ji W, Liu D, Zhang G, Yao R, Xu Y, Yao J.   +10 more
europepmc   +1 more source

Quantum machine learning driven optimization of nutrient-hormone interactions for enhanced in vitro regeneration of common bean. [PDF]

BMC Plant Biol
Katırcı R, Aasim M, Aadil F, Chohan RT.   +3 more
europepmc   +1 more source

Physical activity-associated extracellular vesicles inhibit inflammagen-induced microglial activation. [PDF]

Brain Behav Immun Health
Su CY, Hsu HJ, Wang TF, Chou HL, Tsai SF, Lee CW, Cheng CL, Wang YK, Kuo YM.   +8 more
europepmc   +1 more source

<i>Meta</i>-Topolin as an Aromatic Cytokinin for <i>In Vitro</i> Propagation of <i>Thymus vulgaris</i> L. [PDF]

Plants (Basel)
Mabotja MB, Aremu AO, Doležal K, Ruzvidzo O, Amoo SO.   +4 more
europepmc   +1 more source