Results 181 to 190 of about 160,408 (307)

Exclusive enteral nutrition containing transforming growth factor‐β improves intestinal barrier function in a colitis mouse model

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Exclusive enteral nutrition (EEN) is the first‐line treatment for pediatric Crohn's disease, but its mechanisms of action remain poorly understood. Our aim was to identify the mechanisms that could explain the anti‐inflammatory effects of EEN, studying the nutritional composition and transforming growth factor‐β (TGF‐β) effects, in ...
Kawthar Boumessid   +6 more
wiley   +1 more source

Early‐life adverse events and risk of inflammatory bowel disease: A Scandinavian birth cohort study

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives The experience of childhood stressful or adverse life events is believed to imprint on immunological pathways and, therefore, might have lasting effects on inflammatory bowel disease (IBD) development. This study aimed to examine the association between experiences of early‐life adverse events and later IBD risk. Methods We followed
Ida Sigvardsson   +6 more
wiley   +1 more source

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti‐tumor necrosis factor alpha therapy in children

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in pediatric inflammatory bowel disease (PIBD) with biologics, remission rates remain at 47%–60% with loss‐of‐response rates at 60%–68%. Evidence for efficacy of dual biologic therapy (DBT) with anti‐tumor necrosis factor alpha therapy (anti‐TNF‐α)‐ vedolizumab (VDZ) for children refractory to anti‐TNF‐α therapy is ...
Jonathan E. M. O'Donnell   +6 more
wiley   +1 more source

Population genomics, demography, and circum-Baltic connectivity of Early Medieval southwestern Finland. [PDF]

open access: yesGenome Biol
O'Sullivan RJ   +12 more
europepmc   +1 more source

Growth and development in paediatric onset inflammatory bowel disease: Data analysis from the CEDATA registry

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective Different therapies may affect the growth and development of children and adolescents with inflammatory bowel disease (IBD) supporting specific therapy algorithms for paediatric Crohn's disease (CD) and ulcerative colitis (UC). Methods Growth and development data from the German–Austrian CEDATA‐GPGE registry entered between 2004 and ...
Ilse Broekaert   +4 more
wiley   +1 more source

Inflammatory bowel disease treatment: Mechanisms to clinical translation (Review). [PDF]

open access: yesInt J Mol Med
Tang S   +8 more
europepmc   +1 more source

Anaemia in patients diagnosed with paediatric‐onset inflammatory bowel disease: A Danish nationwide cohort study

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Anaemia impairs daily activities and quality of life in patients with paediatric‐onset inflammatory bowel disease (PIBD). This study aimed to investigate the prevalence of anaemia at PIBD‐diagnosis and the following 5 years. Furthermore, anaemia subtypes and the association between anaemia and disease activity were assessed over ...
Julie Rahbek Norup   +3 more
wiley   +1 more source

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