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Processing of Infectious Bursal Disease Virus (IBDV) Polyprotein and Self-Assembly of IBDV-Like Particles in Hi-5 Cells

Biotechnology Progress, 2006
The capsid of infectious bursal disease virus (IBDV), with a size of 60-65 nm, is formed by an initial processing of polyprotein (pVP2-VP4-VP3) by VP4, subsequent assemblage of pVP2 and VP3, and the maturation of VP2. In Sf9 cells, the processing of polyprotein expressed was restrained in the stage of VP2 maturation, leading to a limited production of ...
Jin-Yi Ho   +4 more
openaire   +3 more sources

Efficacy of Single Dose Recombinant Herpesvirus of Turkey Infectious Bursal Disease Virus (IBDV) Vaccination against a Variant IBDV Strain

Avian Diseases Digest, 2009
The use of viral vectors for transgenic expression of immunogenic proteins is a current trend in the poultry industry. The objective of this work was to assess the protection against the variant E of infectious bursal disease virus (IBDV), conferred by day-one vaccination with a commercial recombinant herpesvirus of turkey (HVT) vaccine (VAXXITEK ...
Rafael Fernández   +4 more
openaire   +2 more sources

Determination of Optimum Formulation of a Novel Infectious Bursal Disease Virus (IBDV) Vaccine Constructed by Mixing Bursal Disease Antibody with IBDV

Avian Diseases, 1995
A novel vaccine against infectious bursal disease virus (IBDV) has been developed. The new vaccine was constructed by mixing bursal disease antibody (BDA) contained in whole antiserum with live IBDV before lyophilization. To establish various formulations of BDA and IBDV, several BDA doses between 5 units and 80 units of BDA/50 microliters were mixed ...
P. D. Andrews   +8 more
openaire   +3 more sources

Generation of a novel attenuated IBDV vaccine strain by mutation of critical amino acids in IBDV VP5

Vaccine
Infectious bursal disease virus (IBDV) is an acute and highly infectious RNA virus known for its immunosuppressive capabilities, chiefly inflicting rapid damage to the bursa of Fabricius (BF) of chickens. Current clinical control of IBDV infection relies on vaccination.
Hui Gao   +9 more
openaire   +2 more sources

Protective Efficacy of Intermediate and Intermediate Plus Infectious Bursal Disease Virus (IBDV) Vaccines Against Very Virulent IBDV in Commercial Broilers

Avian Diseases, 2005
The evolution of very virulent (vv) infectious bursal disease virus (IBDV) has led to significant economic losses in many poultry-producing areas. Despite vigorous vaccination strategies, IBDV has been difficult to control. The protective efficacy of IBDV vaccines is traditionally evaluated in specific pathogen-free (SPF) chickens.
Enrique Montiel   +3 more
openaire   +3 more sources

Studies on Interferon Induction by Infectious Bursal Disease Virus (IBDV). II. Interferon Production in White Leghorn Chickens Infected with an Attenuated or Pathogenic Isolant of IBDV

Avian Diseases, 1979
Infectious bursal disease virus (IBDV) isolants that differed in virulence for chickens, were compared as to: 1) induction of interferon in serum and tissues; and 2) stimulation of IBDV serum antibody. Specific-pathogen-free chickens were infected at one day and four weeks of age by the subcutaneous and intranasal routes of inoculation.
Stanley H. Kleven   +3 more
openaire   +3 more sources

Optineurin inhibits IBDV replication via interacting with VP1

Veterinary Microbiology
Avibirnavirus, specifically Infectious Bursal Disease Virus (IBDV), is a highly contagious pathogen that causes significant economic losses in the poultry industry. The polymerase protein VP1 of IBDV is critical to the viral life cycle, facilitating the synthesis of viral mRNA and the genome.
Zhixuan, Xiong   +4 more
openaire   +2 more sources

Assessment of genetic, antigenic and pathotypic criteria for the characterization of IBDV strains

Avian Pathology, 2004
The aim of this work was the selection and comparison of representative infectious bursal disease virus (IBDV) strains. Nine strains of IBDV, isolated at different times and from different geographic regions of Europe and China, were characterized. Batches of all strains were prepared following standardized protocols and checked for the absence of ...
Zierenberg, K   +14 more
openaire   +4 more sources

Biological and physico-chemical properties of the infectious bursal disease virus (IBDV)

Avian Pathology, 1973
Some biological properties of an egg-adapted strain of IBDV, PV1, have been studied. By immunofluorescent staining the strain is serologically identical to another egg-adapted strain, MU2, and to three pathogenic strains of IBDV. All five strains do not react with antisera prepared against known avian viruses of various groups, including Reoviruses ...
F Cancellotti, P N D'Aprile, M Petek
openaire   +3 more sources

Molecular characterisation of IBDV isolates in Turkey revealed reassortant strains

British Poultry Science
1. Infectious bursal disease (IBD) is an acute, highly contagious viral disease of chickens caused by a virus (IBDV) which has a bi-segmented, double-stranded RNA genome. It has five viral proteins in its structure; the VP1 gene is encoded in segment B and the other four are in segment A.2.
G. A. Kurtbeyoğlu, M. Akan
openaire   +2 more sources

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