Results 81 to 90 of about 20,878 (216)

Descriptive Analysis of Dosing and Outcomes for Patients with Ibrutinib-Treated Relapsed or Refractory Chronic Lymphocytic Leukemia in a Canadian Centre [PDF]

, 2019
Kelsey Uminski, Kevin Brown, Oliver Bucher, Irena Hibbert, Dhali H.S. Dhaliwal, James B. Johnston, Marc Geirnaert, David E. Dawe, Versha Banerji   +8 more
openalex   +1 more source

Healthcare Resource Utilization and Costs in Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia Treated With Covalent Bruton's Tyrosine Kinase Inhibitors: Real‐World Impact of Cardiovascular Adverse Events

Cancer Medicine, Volume 14, Issue 24, December 2025.
ABSTRACT Introduction Although covalent Bruton's tyrosine kinase inhibitors (cBTKis) have transformed treatment of chronic lymphocytic leukemia and small lymphocytic leukemia (CLL/SLL), cBTKi‐related cardiotoxicity is a known side effect. This real‐world study evaluated incident cardiovascular adverse events (CVAE), healthcare resource utilization ...
Mavis Obeng‐Kusi, Enrico De Nigris, Siyang Leng, Mohammed Z. H. Farooqui, Halit O. Yapici, Ian Weimer, Weiqi Jiao, Hayden W. Hyatt, Xuan Zhang, Kunal Lodaya, David Dingli   +10 more
wiley   +1 more source

Efficacy and safety of ibrutinib in Japanese patients with relapsed or refractory mantle cell lymphoma [PDF]

, 2016
Dai Maruyama, Hirokazu Nagai, Noriko Fukuhara, Toshiyuki Kitano, Takayuki Ishikawa, Hirohiko Shibayama, Ilseung Choi, Kiyohiko Hatake, Toshiki Uchida, Momoko Nishikori, Tomohiro Kinoshita, Yoshihiro Matsuno, Tomoaki Nishikawa, Satoko Takahara, Kensei Tobinai   +14 more
openalex   +1 more source

Data from In Human Visualization of Ibrutinib-Induced CLL Compartment Shift

, 2023
Marius E. Mayerhoefer, Alexander Haug, Ulrich Jäger, Verena Pichler, Sarah Pfaff, Hans‐Jürgen Wester, Marcus Hacker, Lukas Kazianka, Philipp B. Staber   +8 more
openalex   +1 more source

Zanubrutinib Combined With Rituximab in the Treatment of Bing‐Neel Syndrome: A Case Report

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Bing‐Neel syndrome (BNS) is a rare complication of Waldenström macroglobulinemia, a condition with low incidence in clinical practice and prone to misdiagnosis. Vigilance is crucial for identifying this condition in patients with Waldenström macroglobulinemia presenting with neurological symptoms.
Rongyao Zhang, Juan Chang, Yanqun Shen, Ping Hu, Lulu Zhang   +4 more
wiley   +1 more source

Integrated pathway analysis identifies prognostically relevant subtypes of glioblastoma characterized by abnormalities in multi‐omics

Clinical and Translational Medicine, Volume 15, Issue 12, December 2025.
We report the interaction between tumour cells and environmental immune cells, classifying GBM into two main subtypes: (1) The tumour‐driving subtype is characterized by multiple oncogenic mutations, while (2) the immune‐blockage subtype is marked by a high presence of immune cells.
Pei Zhang, Dan Liu, Tonghui Yu, Yanlin Zhang, Lu Zhong, Xiao Ouyang, Qin Xia, Lei Dong   +7 more
wiley   +1 more source

Next‐Generation Proteolysis‐Targeting Chimeras in Precision Oncology: Multifunctional Designs, Emerging Modalities, and Translational Prospects in Targeted Protein Degradation

Drug Development Research, Volume 86, Issue 8, December 2025.
ABSTRACT Proteolysis‐targeting chimeras (PROTACs)‐mediated protein degradation has been recently developed as a game‐changing approach in oncology drug development. It represents a paradigm shift from traditional enzyme inhibition to selective protein degradation.
Mohamed S. Nafie, Mohamed K. Diab, Asmaa S. A. Yassen, Amany M. Elshamy, Mohamed R. El Tohamy, Haytham O. Tawfik, Sherif Ashraf Fahmy   +6 more
wiley   +1 more source

Lee J, Zhang LL, Wu W, et al. Activation of MYC, a bona fide client of HSP90, contributes to intrinsic ibrutinib resistance in mantle cell lymphoma. Blood Adv. 2018;2(16):2039-2051. [PDF]

, 2018

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Arrhythmia Patterns in Patients on Ibrutinib [PDF]

, 2022
Muhammad Fazal, Ridhima Kapoor, Paul Cheng, Albert J. Rogers, Sanjiv M. Narayan, Paul J. Wang, Ronald Witteles, Alexander C. Perino, Tina Baykaner, June‐Wha Rhee   +9 more
openalex   +1 more source

Extracorporeal Photopheresis for Chronic Graft‐Versus‐Host Disease According to 2014 NIH Consensus Criteria

Journal of Clinical Apheresis, Volume 40, Issue 6, December 2025.
ABSTRACT Chronic graft‐versus‐host disease (cGVHD) remains a major cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation. Many cGVHD patients require prolonged systemic immunosuppression with corticosteroids, which carry significant adverse effects, and alternative therapies are often required.
Yitzhar Goretsky, Noa Holtzman, Sunwoo Han, Isildinha M. Reis, Vera Suzuki, Pepita Jean, Karla Mones, Meilin Diaz‐Paez, Cara Benjamin, Amer Beitinjaneh, Mark Goodman, Antonio Jimenez Jimenez, Lazaros Lekakis, Denise Pereira, Jay Spiegel, Yanyun Wu, Damian J. Green, Krishna V. Komanduri, Trent P. Wang   +18 more
wiley   +1 more source