Results 81 to 90 of about 25,366 (193)
Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors
Advanced Science, Volume 13, Issue 11, 23 February 2026.This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su +15 more
wiley +1 more source
Initial-boundary value problems for integrable evolution equations with $3 \times 3$ Lax pairs
, 2012 We present an approach for analyzing initial-boundary value problems for integrable equations whose Lax pairs involve $3 \times 3$ matrices. Whereas initial value problems for integrable equations can be analyzed by means of the classical Inverse ...
Lenells, Jonatan
core +1 more source
Coronavirus IBV: Structural Characterization of the Spike Protein
Journal of General Virology, 1983 The spike protein (S; surface projection) of avian infectious bronchitis virus (IBV) strain M41 comprises two glycopolypeptides, S1 (mol. wt. 90 X 10(3] and S2 (mol. wt. 84 X 10(3], in equimolar proportions. The apparent mol. wt. of S was calculated as 354 (+/- 17) X 10(3) following co-sedimentation with catalase in sucrose gradients.
openaire +2 more sources
Clinical and Experimental Dental Research, Volume 12, Issue 1, February 2026.ABSTRACT Objectives Hypericum perforatum L. offers several beneficial effects, for example antioxidant, antitumor, wound healing. Our aim was to ascertain the effect of H. perforatum extract gum on salivary Streptococcus mutans count, pH, plaque index, and gingival bleeding. Materials and Methods A total of 54 participants were assigned into two groups
Aylin Jamali +5 more
wiley +1 more source
Polariton Condensation and Lasing
, 2012 The similarities and differences between polariton condensation in microcavities and standard lasing in a semiconductor cavity structure are reviewed. The recent experiments on "photon condensation" are also reviewed.Comment: 23 pages, 6 figures; Based ...
A Amo +27 more
core +1 more source
Astrocyte Senescence Impairs Synaptogenesis due to Thrombospondin‐1 Loss
Aging Cell, Volume 25, Issue 2, February 2026.Senescent hippocampal astrocytes lose TSP secretion, impairing excitatory synaptogenesis via the α2δ‐1 pathway. Restoring TSP‐1 rescues synaptic formation, revealing the contribution of astrocyte senescence to age‐related hippocampal synaptic decline.
Stefano Ercoli +3 more
wiley +1 more source
eLifeEvolutionary transitions from egg laying (oviparity) to live birth (viviparity) are common across various taxa. Many species also exhibit genetic variation in egg-laying mode or display an intermediate mode with laid eggs containing embryos at various ...
Laure Mignerot +6 more
doaj +1 more source
On singular perturbations for quasilinear IBV problems [PDF]
Annales de la Faculté des sciences de Toulouse : Mathématiques, 2000 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Influenza and Other Respiratory Viruses, Volume 20, Issue 2, February 2026.ABSTRACT Background Influenza B virus (IBV) contributes to seasonal epidemics, but its molecular evolution is less defined than influenza A. We analyzed IBVs collected in Japan and Myanmar (2016–2020) to investigate lineage dynamics, reassortment, and genetic mismatch with vaccine strains. Methods Respiratory specimens from patients with influenza‐like
Yusuke Ichikawa +16 more
wiley +1 more source
FEBS Letters, Volume 600, Issue 2, Page 251-266, January 2026.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source