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Struktura a funkce proteinů CAD-ICAD
Caspase-activated DNase (CAD) and its inhibitor (ICAD) are essential regulators of apoptosis, playing a pivotal role in DNA fragmentation and cellular disintegration. Under proapoptotic conditions, caspase-3 cleaves ICAD within the CAD-ICAD heterodimer, releasing CAD to form homodimers which induce double-strand breaks (DSBs) in nuclear DNA.openaire +1 more source
ICAD: An Intelligent Framework for Real-Time Criminal Analytics and Detection
2023Raed Abdallah +4 more
openaire +1 more source
Functional Differences of Two Forms of the Inhibitor of Caspase-activated DNase, ICAD-L, and ICAD-S
Journal of Biological Chemistry, 1999Shigekazu Nagata +2 more
exaly
Identification of ICAD‐derived peptides capable of inhibiting caspase‐activated DNase
FEBS Journal, 2012Albert Jeltsch
exaly
Endovascular treatment for AIS with underlying ICAD
Journal of NeuroInterventional Surgery, 2017Sami Al Kasab +2 more
exaly

