Results 261 to 270 of about 27,302,336 (342)

Serum levels of PECAM-1, ICAM-1, and VCAM-1 in patients with systemic lupus erythematosus: associations with disease activity and clinical features from a single-center study. [PDF]

Rheumatol Int
Rybka G, Węglarczyk K, Dziedzic R, Siedlar M, Korkosz M, Kosałka-Węgiel J.   +5 more
europepmc   +1 more source

Hyaluronic Acid Decoration Facilitates CD44‐Mediated Targeting and Alters Protein Corona Formation of Extracellular Vesicles

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Cell recognition and uptake of extracellular vesicles (EVs) is mediated by a variety of surface molecules. Growing interest has recently been drawn towards glycan structures on EVs. Hyaluronic acid (HA) is a negatively charged glycosaminoglycan that can decorate the surface of EVs from different origins.
Heikki Kyykallio, Elena Scurti, Martina Hanzlíková, Kirsti Härkönen, Tuovi Salo, Veera Keinonen, Janne Capra, Tapani Viitala, Jaakko Teppo, Tatu Lajunen, Kirsi Rilla   +10 more
wiley   +1 more source

Therapeutic Galectin‐3 Apheresis Improves Sepsis Outcomes Through Coordinated Neutrophil Modulation and Endothelial Barrier Preservation: A Translational Study

MedComm, Volume 7, Issue 4, April 2026.
Gal‐3 apheresis reduces neutrophil hyperactivation (CXCL2/CXCL8, MPO, NETs), preserves endothelial barrier function (tight junctions, vWF/VCAM‐1/ICAM‐1), and attenuates PI3K/AKT/HIF‐1α signaling. These coordinated effects significantly improve hemodynamics, reduce pulmonary edema (ELWI), lower vasopressor and fluid requirements, and increase survival ...
Zhongyi Sun, Jiachen Qu, Sheng Peng, Yanan Hu, Amity Eliaz, Glenn M. Chertow, Isaac Eliaz, Zhiyong Peng   +7 more
wiley   +1 more source

Purslane (Portulaca oleracea L.) Extract Alleviates Atherosclerosis in ApoE−/− Mice

Molecular Nutrition &Food Research, Volume 70, Issue 7, 15 April 2026.
Oral administration of purslane extract at 400 mg/lg/day for 4 weeks reduces atherosclerotic plaque formation, endothelial dysfunction, and vascular inflammation through suppressing the MAPK pathway and activating AMPK/PI3K/Akt/eNOS pathway in ApoE−/− mice. ABSTRACT Portulaca oleracea L.
Yuehan Wang, Junming Chen, Hua Yu, Yuanshan Yu, Manqin Fu, Wai San Cheang   +5 more
wiley   +1 more source

High Intraocular Concentration of Fibrinogen Regulates Retinal Function Via the ICAM-1 Pathway. [PDF]

Invest Ophthalmol Vis Sci
Sotani Y, Imai H, Yamada H, Miki A, Kusuhara S, Nakamura M.   +5 more
europepmc   +1 more source

Crohn's lymphoid aggregates with endothelial clusters colocalise with submucosal fibrosis in fibrostenosing Crohn's disease

The Journal of Pathology, Volume 268, Issue 4, Page 398-412, April 2026.
Abstract Crohn's disease (CD) involves chronic transmural inflammation of the intestines, leading to progressive wall fibrosis with stenosis and luminal obstruction, predominantly in the terminal ileum. Fibrosis is a significant therapeutic challenge, thus improved understanding of localisation, cellular composition, and cell–cell interactions in CD ...
Michael Glinka, Gregory J Wickham, Francesca Nadalin, Kathryn J Kirkwood, Helen Caldwell, Mike Wicks, Bill Hill, Derek Houghton, Mehran Sharghi, Amirhosein Kefayat, Bernard Haggarty, Albert Burger, Richard A Baldock, David J Adams, Irene Papatheodorou, Peter Bankhead, Shahida Din, Mark J Arends   +17 more
wiley   +1 more source

Evaluation of Circulating Levels of ICAM-1 in Obstructive Sleep Apnea (OSA) Adults: Systematic Review, Meta-Analysis, and Trial Sequential Analysis of Link Between OSA and Cardiovascular Disease. [PDF]

Life (Basel)
Imani MM, Imani A, Sadeghi M, Brühl AB, Brand S.   +4 more
europepmc   +1 more source

Hydrogen‐Enriched Hyaluronic Acid Dressing Ameliorates Diabetic Foot Ulcer via Promoting Mitophagy

Journal of Diabetes, Volume 18, Issue 4, April 2026.
The combination of VSD and hydrogen‐rich saline is used to treat diabetic foot ulcers. In vitro and in vivo studies reveal that hydrogen‐enrich hyaluronic acid dressings enhance skin fibroblast repair ability by regulating mitophagy via the SIRT3 and its downstream signaling pathways, ultimately accelerating wound healing in diabetic foot ulcers ...
Ziyu Xu, Xinyu Cui, Houbin Chu, Hao Wan, Yunbo Xie, Ying Wang, Qingbin Ni, Xiaolin Ding, Guohua Song   +8 more
wiley   +1 more source

Tumor‐Bearing Status Accelerates Bleomycin‐Induced Pulmonary Inflammation via Endothelial Activation

Thoracic Cancer, Volume 17, Issue 7, April 2026.
In subcutaneous tumor‐bearing mice, inflammatory cell infiltration into the lung was aggravated via endothelial activation. The tumor‐bearing status additively aggravated BLM‐induced lung inflammation. Proinflammatory changes in the lungs accelerated by tumor‐bearing status might be involved in the development of drug‐induced lung inflammation ...
Shoko Isoyama, Kakuhiro Yamaguchi, Hiroshi Iwamoto, Yasushi Horimasu, Kunihiko Funaishi, Kiyofumi Shimoji, Shinjiro Sakamoto, Takeshi Masuda, Taku Nakashima, Shinichiro Ohshimo, Hironobu Hamada, Noboru Hattori   +11 more
wiley   +1 more source

Extracellular vesicle surface engineering with integrins (ITGAL & ITGB2) to specifically target ICAM-1-expressing endothelial cells. [PDF]

J Nanobiotechnology
Bergqvist M, Park KS, Karimi N, Yu L, Lässer C, Lötvall J.   +5 more
europepmc   +1 more source