Results 261 to 270 of about 159,080 (332)

Activation of USP30 Disrupts Endothelial Cell Function and Aggravates Acute Lung Injury Through Regulating the S‐Adenosylmethionine Cycle

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
USP30 deubiquitinates and stabilizes MAT2A, thereby regulating DNA methylation and miRNA expression, which ultimately leads to disruption of lung endothelial barrier and inflammation. Abstract Microvascular dysfunction is a key contributor to the development of acute inflammatory diseases, characterized by heightened vascular hyperpermeability and ...
Baoyinna Baoyinna   +11 more
wiley   +1 more source

Fever Inspiration: Precision Engineering for Safe and Systemic Immunotherapy

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
This review examines engineered fever therapy (EFT) as a novel cancer treatment, harnessing fever's immunomodulatory effects to enhance systemic immune responses. It explores molecular mechanisms, advances in nanotechnology‐driven thermal immunotherapy, and a bioengineered framework for precise, safe fever induction. The paper evaluates EFT's potential
Yang Li   +5 more
wiley   +1 more source

9‐Deoxymuzigadial, a Sesquiterpene Isolated From Drimys brasiliensis (Winteraceae), Displays Reduced Cytotoxicity In Vitro and Modulates Leukocyte Activity and Fibrogenesis In Vivo

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT The aims of this study were to investigate in vitro cytotoxic potential and the effects of daily administration during the inflammatory response induced by sponge implants in mice of the sesquiterpene 9‐deoxymuzigadial (9‐DOM), isolated from Drimys brasiliensis (Winteraceae).
Bruno Antonio Ferreira   +7 more
wiley   +1 more source

New Cellular Models to Support Preclinical Studies on ICAM-1-Targeted Drug Delivery. [PDF]

open access: yesJ Drug Deliv Sci Technol
Vigo M   +5 more
europepmc   +1 more source

MOESM2 of ICAM-1-related long non-coding RNA: promoter analysis and expression in human retinal endothelial cells

open access: gold, 2018
Amanda L. Lumsden   +6 more
openalex   +1 more source

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