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ICAM-1 and VCAM-1: gatekeepers in various inflammatory and cardiovascular disorders.
Clinica chimica acta; international journal of clinical chemistry, 2023Leukocyte migration from the vascular compartment is critical fornormal lymphocyte recirculation in specific tissues and immune response in inflammatory locations. Leukocyte recruitment, migration to inflammatory areas, and targeting in the extravascular
Varinder Singh +4 more
semanticscholar +1 more source
Gene regulation of Intracellular adhesion Molecule-1 (ICAM-1): A molecule with multiple functions.
Immunology Letters, 2021Intracellular adhesion molecule 1 (ICAM-1) is one of the most extensively studied inducible cell adhesion molecules which is responsible for several immune functions like T cell activation, extravasation, inflammation, etc. The molecule is constitutively
Mona Singh +9 more
semanticscholar +1 more source
Tissue & Cell, 2018
Alterations of Endothelial cells (ECs) play a critical role in different pathogenesis of many serious human diseases, and dysfunction of the vascular endothelium is an indicator for human disorders.
K. Habas, L. Shang
semanticscholar +1 more source
Alterations of Endothelial cells (ECs) play a critical role in different pathogenesis of many serious human diseases, and dysfunction of the vascular endothelium is an indicator for human disorders.
K. Habas, L. Shang
semanticscholar +1 more source
A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.
Journal of Immunology, 1986Homotypic adhesion by phorbol ester-stimulated lymphocytes requires LFA-1 and Mg+2 and does not involve like-like interactions between LFA-1 molecules on adjacent cells.
R. Rothlein +3 more
semanticscholar +1 more source
ICAM-1 signaling in endothelial cells
Pharmacological Reports, 2009Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines.
Charlotte, Lawson, Sabine, Wolf
openaire +2 more sources
miR-335-5p targeting ICAM-1 inhibits invasion and metastasis of thyroid cancer cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018miRNAs is a kind of noncoding small RNAs with negative regulation function. Some miRNAs play a crucial role in the growth of tumor cells. In this study, we analyzed the role of miR-335-5p and its target gene intercellular adhesion molecule 1 (ICAM-1) in ...
Li Luo +12 more
semanticscholar +1 more source

