Molecules, 2011 Icariin had been reported as a potential agent for osteogenesis, but the dose-effect relationship needed further research to realize the clinical application of icariin.
Zhi-yong Zhang
exaly +3 more sources
Icariin promotes osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) by activating PI3K-AKT-UTX/EZH2 signaling in steroid-induced femoral head osteonecrosis [PDF]
Journal of Orthopaedic Surgery and ResearchBackground Differentiation of bone marrow mesenchymal stem cells (BMSCs) is pivotal in the pathogenesis of steroid-induced femoral head osteonecrosis.
Wei Ji +5 more
doaj +2 more sources
Sexual enhancement products for sale online : raising awareness of the psychoactive effects of Yohimbine, Maca, Horny Goat Weed and Ginkgo Biloba [PDF]
, 2014 Copyright © 2014 Ornella Corazza et al.This is an open access article distributed under theCreativeCommonsAttribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Eleonora Chillemi +6 more
core +19 more sources
Frontiers in Bioengineering and Biotechnology, 2022 Bone morphogenetic protein (BMP) pathway is essential for M2 macrophage polarization and hair-follicle neogenesis. Icariin, a flavonoid derived from Epimedium, is a mediator of the BMP pathway.
Ying-Ying Teng +12 more
doaj +1 more source
Effects of icariin on the fracture healing in young and old rats and its mechanism
Pharmaceutical Biology, 2021 Context Icariin has attracted increasing attention because of its wide variety of pharmacological effects. Objective This study investigates whether icariin could promote fracture healing in young and old rats and its mechanisms.
Xiaoyun Zhang +8 more
doaj +1 more source
Odontogenic Effect of Icariin on the Human Dental Pulp Cells
Medicina, 2022 Background and Objectives: Human dental pulp cells (HDPCs) can be used for dentin regeneration due to its odontogenic differentiation property. Icariin can induce osteogenic differentiation of stem cells.
Guo Liu +4 more
doaj +1 more source
Icariin induces synoviolin expression through NFE2L1 to protect neurons from ER stress-induced apoptosis. [PDF]
PLoS ONE, 2015 By suppressing neuronal apoptosis, Icariin is a potential therapeutic drug for neuronal degenerative diseases. The molecular mechanisms of Icariin anti-apoptotic functions are still largely unclear.
Fei Li +4 more
doaj +1 more source
Comparison of chemical profiles and effectiveness between Erxian decoction and mixtures of decoctions of its individual herbs : a novel approach for identification of the standard chemicals [PDF]
, 2017 Acknowledgements This study was partially supported by grants from the Seed Funding Programme for Basic Research (Project Number 201211159146 and 201411159213), the University of Hong Kong.
Cheung, H. P. +8 more
core +4 more sources
Ameliorating effect of Erxian decoction combined with Fructus Schisandrae chinensis (Wu Wei Zi) on menopausal sweating and serum hormone profiles in a rat model [PDF]
, 2016 Additional file 3.
Ai Hua Liu +10 more
core +6 more sources
Innate Immunity, 2020 In this study, we used LS174T cells as a model to investigate the protective effects of icariin and phosphorylated icariin on LPS-induced goblet cell dysfunction.
Wen Xiong +6 more
doaj +1 more source