Results 1 to 10 of about 7,242 (224)
Icariin Metabolism by Human Intestinal Microflora [PDF]
Molecules, 2016 Icariin is a major bioactive compound of Epimedii Herba, a traditional oriental medicine exhibiting anti-cancer, anti-inflammatory and anti-osteoporosis activities.
Mihyang Kim, Jaehong Han
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Effects of Icariin on Reproductive Functions in Male Rats [PDF]
Molecules, 2014 The present study investigated the effects and potential mechanism(s) of action of icariin on the reproductive functions of male rats. Adult rats were treated orally with icariin at doses of 0 (control), 50, 100, or 200 mg/kg body weight for 35 ...
Gang Li
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Molecules, 2011 Icariin had been reported as a potential agent for osteogenesis, but the dose-effect relationship needed further research to realize the clinical application of icariin.
Zhi-yong Zhang
exaly +3 more sources
Icariin promotes osteogenic differentiation by upregulating alpha-enolase expression
Biochemistry and Biophysics Reports, 2023 Osteogenic differentiation is a crucial biological process for maintaining bone remodelling. Aerobic glycolysis is the main source of energy for osteogenic differentiation.
Dingbang Xie +8 more
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Icariin promotes osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) by activating PI3K-AKT-UTX/EZH2 signaling in steroid-induced femoral head osteonecrosis [PDF]
Journal of Orthopaedic Surgery and ResearchBackground Differentiation of bone marrow mesenchymal stem cells (BMSCs) is pivotal in the pathogenesis of steroid-induced femoral head osteonecrosis.
Wei Ji +5 more
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Frontiers in Bioengineering and Biotechnology, 2022 Bone morphogenetic protein (BMP) pathway is essential for M2 macrophage polarization and hair-follicle neogenesis. Icariin, a flavonoid derived from Epimedium, is a mediator of the BMP pathway.
Ying-Ying Teng +12 more
doaj +1 more source
Odontogenic Effect of Icariin on the Human Dental Pulp Cells
Medicina, 2022 Background and Objectives: Human dental pulp cells (HDPCs) can be used for dentin regeneration due to its odontogenic differentiation property. Icariin can induce osteogenic differentiation of stem cells.
Guo Liu +4 more
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Effects of icariin on the fracture healing in young and old rats and its mechanism
Pharmaceutical Biology, 2021 Context Icariin has attracted increasing attention because of its wide variety of pharmacological effects. Objective This study investigates whether icariin could promote fracture healing in young and old rats and its mechanisms.
Xiaoyun Zhang +8 more
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Icariin induces synoviolin expression through NFE2L1 to protect neurons from ER stress-induced apoptosis. [PDF]
PLoS ONE, 2015 By suppressing neuronal apoptosis, Icariin is a potential therapeutic drug for neuronal degenerative diseases. The molecular mechanisms of Icariin anti-apoptotic functions are still largely unclear.
Fei Li +4 more
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PLGA scaffold carrying icariin to inhibit the progression of osteoarthritis in rabbits [PDF]
Royal Society Open Science, 2019 Icariin, the main effective component extracted from epimedium, has been shown to stimulate osteogenic differentiation and bone formation and to increase synthesis of the cartilage extracellular matrix. However, there has been little study on the effects
Chang Fu Zhao +5 more
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