Results 31 to 40 of about 7,149 (225)
Frontiers in Pharmacology, 2021 Tubulointerstitial fibrosis is one of the most common pathological features of diabetic nephropathy. Autophagy, an intracellular mechanism to remove damaged or dysfunctional cell parts and maintain metabolic homeostasis, is inhibited in diabetic ...
Zhirong Jia +7 more
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Icariin reduces human colon carcinoma cell growth and metastasis by enhancing p53 activities
Brazilian Journal of Medical and Biological Research, 2018 Icariin has been reported to possess high anticancer activity. Colon carcinoma is one of the leading causes of cancer-related mortality worldwide. Here, the anticancer activity of icariin against HCT116 colon carcinoma cells and the possible underlying ...
Meili Tian, Shuang Yang, Xinpeng Yan
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Multi-nutrient supplement improves hormone ratio associated with cancer risk. [PDF]
, 2013 BACKGROUND: Gynecological cancers are among the most common in women and are directly related to a variety of hormonal factors. One potential risk factor associated with developing a gynecological malignancy is the ratio of two hormone metabolites, 2 ...
Bazzan, MD, Anthony J +2 more
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Brazilian Journal of Pharmaceutical Sciences, 2019 Icariin, a prenylated flavonol glycoside isolated from Epimedium, has been considered as a potential alternative therapy for osteoporosis. The present study aimed to clarify the detailed molecular mechanisms of action of icariin on osteoblast function ...
Dan Lou +5 more
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Inhibition of Th1 and Th17 Cells by Medicinal Plants and Their Derivatives: A Systematic Review. [PDF]
, 2017 Searching for new natural drugs that are capable of targeting Th1 and Th17 may lead to development of more effective treatments for inflammatory and autoimmune diseases.
Asadi-Samani, Majid. +3 more
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Frontiers in Physiology, 2017 Icariin, a flavonoid monomer from Herba Epimedii, has confirmed pharmacological and biological effects. However, its effects on arrhythmias and cardiac electrophysiology remain unclear.
Wanzhen Jiang +8 more
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A review on antidepressant effect of medicinal plants [PDF]
, 2017 Depression is a life-threatening, debilitating, and common disease affecting different segments of community. Chemical and synthetic drugs available to treat this disease cause many adverse effects and may lead to complete recovery in only 50% of ...
Rabie, S., Rabiei, Z.
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Frontiers in Oncology, 2022 PurposeDespite various therapy advances, ovarian cancer remains an incurable disease for which survival rates have only modestly improved. Natural products are important sources of anti-cancer lead compounds. Icariin exhibited broad anti-cancer efficacy.
Yanjin Fu +7 more
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Modulation of neurotrophic signaling pathways by polyphenols [PDF]
, 2015 Polyphenols are an important class of phytochemicals, and several lines of evidence have demonstrated their beneficial effects in the context of a number of pathologies including neurodegenerative disorders such as Alzheimer's and Parkinson's disease. In
Firuzi, Omidreza +3 more
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Identification of the major chemical constituents and their metabolites in rat plasma and various organs after oral administration of effective Erxian Decoction (EXD) fraction by liquid chromatography-mass spectrometry [PDF]
, 2010 A simple and specific LC-DAD-ESI-MS/MS method has been developed and applied for the primary investigation of the chemical constituents absorbed or metabolized in vivo, after the rat oral administration of Erxian Decoction (EXD), a Chinese medicine ...
Hu, YM +7 more
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