Results 91 to 100 of about 6,388,732 (302)

Quantifying coding integrity and reliability of ICD-11 MMS for rare disease registration: a case study of the Chinese rare disease catalogue

BMC Medical Informatics and Decision Making
Introduction Epidemiological data on rare diseases (RDs) affect the accurate scientific assessment of these diseases and lead to many issues in policy-making, healthcare systems, and legislation.
Xue Bai, Jian Guo, Meng Zhang, Yi Wang, Naishi Li   +4 more
doaj   +1 more source

Epitaxially Integrated Electro‐Optic KNbO3 Thin Films on Silicon

Advanced Materials, EarlyView.
We demonstrate the first epitaxial integration of electro‐optic KNbO3 thin films on silicon using suboxide molecular‐beam epitaxy. Combining adsorption‐controlled molecular‐beam epitaxy, advanced characterization, and phase‐field modeling, we demonstrate phase‐pure crystalline films mirroring bulk crystals with robust Pockels response, enabling future ...
Sankalpa Hazra, Tobias Schwaigert, Yingxin Zhu, Aiden Ross, Muhammad Aminul Haque Chowdhury, Shun‐Li Shang, Sameer Singh, Zhiyu Zhang, Zhe Wang, Brynn Brower, Saugata Sarker, Suchismita Sarker, Zi‐Kui Liu, Rama K. Vasudevan, Long‐Qing Chen, Yang Yang, Darrell G. Schlom, Venkatraman Gopalan   +17 more
wiley   +1 more source

Segmented Timber Shells for Circular Construction: Relocation, Structural Assessment, and Robotic Fabrication of a Modular, Lightweight Timber Structure

Buildings
Segmented timber shells present a novel building system that utilizes modular, planar building components to create lightweight free-form structures in architecture.
Simon Bechert, Simon Aicher, Lyudmila Gorokhova, Laura Balangé, Monika Göbel, Volker Schwieger, Achim Menges, Jan Knippers   +7 more
doaj   +1 more source

A psychometric assessment of Disturbances in Self-Organization symptom indicators for ICD-11 Complex PTSD using the International Trauma Questionnaire

European Journal of Psychotraumatology, 2018
Background: Two ‘sibling disorders’ have been proposed for the 11th version of the International Classification of Diseases (ICD-11): Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD).
Mark Shevlin, Philip Hyland, Neil P. Roberts, Jonathan I. Bisson, Chris R Brewin, Marylene Cloitre   +5 more
doaj   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Clinical implications of the proposed ICD-11 PTSD diagnostic criteria [PDF]

, 2018
Background: Projected changes to post-traumatic stress disorder (PTSD) diagnostic criteria in the upcoming International Classification of Diseases (ICD)-11 may affect the prevalence and severity of identified cases.
Barbano, Anna C., Miranda Olff, Kessler, Ronald C., Wei Qi, Kessler, Ronald C, Matsuoka, Yutaka J., Anna C. Barbano, Qi, Wei, Ratanatharathorn, Andrew, Qi, W, Schnyder, Ulrich, Kessler, RC, deRoon-Cassini, Terri A., Koenen, KC, Shalev, Arieh Y., Andrew Ratanatharathorn, Olff, M, Richard A. Bryant, Seedat, Soraya, Matsuoka, Yutaka J, Van Der Mei, WF, Shalev, Arieh Y, Delahanty, DL, Ratanatharathorn, A, Delahanty, Douglas L, Ronald C. Kessler, Shalev, AY, Olff, Miranda, Koenen, Karestan C., Yutaka J. Matsuoka, Soraya Seedat, Barbano, AC, Willem F. van der Mei, Delahanty, Douglas L., Seedat, S, Bryant, Richard A, Bryant, RA, Arieh Y. Shalev, Douglas L. Delahanty, Koenen, Karestan C, Ulrich Schnyder, Schnyder, U, Bryant, Richard A., Terri A. deRoon-Cassini, van der Mei, Willem F., van der Mei, Willem F, Karestan C. Koenen, Matsuoka, YJ, Barbano, Anna C, Deroon-Cassini, TA, deRoon-Cassini, Terri A   +50 more
core   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

Die posttraumatische Belastungsstörung (PTBS) nach dem ICD-11 Kriterienvorschlag bei inhaftierten Männern [PDF]

, 2019
Theoretischer Hintergrund: Die voraussichtlich 2018 erscheinende elfte Version des ICD führt nach der online einsehbaren Betaversion zu veränderten Kriterien hinsichtlich der posttraumatischen Belastungsstörung (PTBS).
Krammer, Sandy, Gamma, Alex, Grosse Holtforth, Martin, Maercker, Andreas, Maercker, Andreas; https://orcid.org/, Liebrenz, Michael   +5 more
core   +1 more source

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

Advanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li, Yijun Ge, Jingxiao Du, Liu Yang, Bangsheng Wu, Chenyue Hang, Mengxi Shen, Yimin Mao, Ting Zhang, Qiyu Bo, Tianyuan Zhao, Yutian Jiao, Yazhi Wang, Shunxiang Gao, Jieqiong Chen, Junran Sun, Tong Li, Huixun Jia, Yang Dou, Wei Cheng, Xiaoling Wan, Jintai Yu, Xiaodong Sun, Bai Lu   +23 more
wiley   +1 more source