Results 61 to 70 of about 306,492 (342)

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Assessment of the Greenland ice sheet–atmosphere feedbacks for the next century with a regional atmospheric model coupled to an ice sheet model

The Cryosphere, 2017
. In the context of global warming, growing attention is paid to the evolution of the Greenland ice sheet (GrIS) and its contribution to sea-level rise at the centennial timescale.
Sébastien Le clec’h, S. Charbit, A. Quiquet, X. Fettweis, C. Dumas, Masa Kageyama, C. Wyard, Catherine Ritz   +7 more
semanticscholar   +1 more source

Calibrating an Ice Sheet Model Using High-Dimensional Binary Spatial Data [PDF]

, 2015
Rapid retreat of ice in the Amundsen Sea sector of West Antarctica may cause drastic sea level rise, posing significant risks to populations in low-lying coastal regions.
Won Chang, M. Haran, P. Applegate, D. Pollard   +3 more
semanticscholar   +1 more source

Modeling Antarctic ice sheet loss [PDF]

Science, 2019
Cryosphere Knowledge of the speed and scale of ice-shelf melting in Antarctica is crucial for estimates of ice sheet loss. How accurate do models need to be to capture these processes and yield useful projections of future ice sheet loss and the resulting sea level rise? To address this question, Goldberg et al.
openaire   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

The GRISLI ice sheet model (version 2.0): calibration and validation for multi-millennial changes of the Antarctic ice sheet

Geoscientific Model Development, 2018
. In this paper, we present the GRISLI (Grenoble ice sheet and land ice) model in its newest revision (version 2.0). Whilst GRISLI is applicable to any given ice sheet, we focus here on the Antarctic ice sheet because it highlights the importance of ...
A. Quiquet, C. Dumas, C. Ritz, V. Peyaud, D. Roche   +4 more
semanticscholar   +1 more source

Laser‐Induced Graphene from Waste Almond Shells

Advanced Functional Materials, EarlyView.
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova, Anna Chiara Bressi, Marina Galliani, Attilio Marino, Gianni Ciofani, Eduardo Machado‐Charry, Hilda Gomez Bernal, Alessandra Francini, Luca Sebastiani, Francesco Greco   +9 more
wiley   +1 more source

Probabilistic calibration of a Greenland Ice Sheet model using spatially resolved synthetic observations: toward projections of ice mass loss with uncertainties [PDF]

Geoscientific Model Development, 2014
Computer models of ice sheet behavior are important tools for projecting future sea level rise. The simulated modern ice sheets generated by these models differ markedly as input parameters are varied.
W. Chang, P. J. Applegate, M. Haran, K. Keller   +3 more
doaj   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

Numerical estimation of 10000 years later equilibrium ice sheet profile in the Shirase Glacier drainage basin, East Antarctica

Antarctic Record, 1991
Recent observations show that the ice sheet in the Shirase Glacier drainage basin, East Antarctica, is thinning. If the observed thinning is assumed to be a transitional process in which the ice sheet is adjusting to the present climate, an equilibrium ...
Shuji Fujita, Norikazu Ikeda, Nobuhiko Azuma, Takeo Hondoh, Shinji Mae   +4 more
doaj   +1 more source