Results 41 to 50 of about 2,666,636 (245)

Modelling Glaciers in the HARMONIE-AROME NWP model [PDF]

Advances in Science and Research, 2017
HARMONIE-AROME is a convection-permitting non-hydrostatic model that includes the multi-purpose SURFEX surface model. It is developed for high resolution (1–3 km) weather forecasting and applied in a number of regions in Europe and the Mediterranean ...
R. Mottram, K. P. Nielsen, E. Gleeson, X. Yang   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

A stratigraphic link across 1100 km of the Antarctic Ice Sheet between the Vostok ice-core site and Titan Dome (near South Pole) [PDF]

, 2000
Isochronous internal ice-sheet layering, measured from airborne 60 MHz radar, was traced between Lake Vostok and the Titan Ice Dome (100 km from South Pole Station), Antarctica. Three layers were selected between Ridge B and Titan Dome, and between Ridge
Siegert, MJ, Hodgkins, R, Siegert, M. J., Hodgkins, R.   +3 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Quantitative sub-ice and marine tracing of Antarctic sediment provenance (TASP v1.0) [PDF]

Geoscientific Model Development
Ice sheet models should be able to accurately simulate palaeo ice sheets to have confidence in their projections of future polar ice sheet mass loss and resulting global sea level rise.
J. W. Marschalek, E. Gasson, T. van de Flierdt, C.-D. Hillenbrand, M. J. Siegert, M. J. Siegert, L. Holder   +6 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Reconstruction of ice-sheet changes in the Antarctic Peninsula since the Last Glacial Maximum [PDF]

, 2014
This paper compiles and reviews marine and terrestrial data constraining the dimensions and configuration of the Antarctic Peninsula Ice Sheet (APIS) from the Last Glacial Maximum (LGM) through deglaciation to the present day.
Glasser, N.F., Davies, Bethan J., Emma P. Hocking (7190990), Larter, Robert D., Larter, R.D., Anderson, J.B., John B. Anderson (7190993), Livingstone, Stephen J., Simms, A.R., Roberts, S.J., Ó Cofaigh, Colm, Domack, E., Evans, J., Hillenbrand, Claus-Dieter, James A. Smith (1496818), Livingstone, Stephen, Michael J. Bentley (7190996), Livingstone, S.J., Dowdeswell, Julian, Anderson, John B., Hocking, Emma, Eugene Domack (6507515), Anderson, John, Canals, M., Canals, Miquel, Roberts, Stephen J., Johnson, J.S., O Cofaigh, C., Stephen J. Roberts (7191008), Hillenbrand, C.D., Larter, Robert, Simms, Alexander, Neil F. Glasser (7191002), Hodgson, Dominic A., Smith, J.A., Julian A. Dowdeswell (7190999), Bentley, Michael J., Colm O Cofaigh (7190984), Jeffrey Evans (1254507), Dowdeswell, Julian A., Hocking, Emma P., Simms, Alexander R., Hillenbrand, Claus Dieter, Hodgson, D.A., Smith, James A., Bentley, M.J., Domack, Eugene, Dowdeswell, J.A., Davies, Bethan, Alexander R. Simms (7191011), Stephen J. Livingstone (3691018), Joanne S. Johnson (7190987), Robert D. Larter (7191005), Johnson, Joanne S., Bentley, Michael, Hodgson, Dominic, Bethan J. Davies (2843855), Glasser, Neil, Miquel Canals (186525), Claus-Dieter Hillenbrand (4276453), Dominic A. Hodgson (2043412), Evans, Jeffrey, Glasser, Neil F., Hillenbrand, C-D., Canals, Miguel, Hocking, E.P., Davies, B.J.   +66 more
core   +1 more source

Basal hydrofractures near sticky patches

Journal of Glaciology, 2023
Basal crevasses are macroscopic structural discontinuities at the base of ice sheets and glaciers that arise by fracture. Motivated by observations and by the mechanics of elastic fracture, we hypothesise that spatial variations in basal stress (in the ...
Hanwen Zhang, Timothy Davis, Richard F. Katz, Laura A. Stevens, Dave A. May   +4 more
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source