Results 131 to 140 of about 3,902,696 (360)

Simulation and investigation of tire tread blocks interaction with ice / Padangos protektoriaus elementų sąveikos su ledu modeliavimas ir tyrimas

Mokslas: Lietuvos Ateitis, 2017
The car tire is an essential subject analysing its interaction with the road. From tire’s tread condition, geometry and rubber compound depends grip and vehicle stability.
Andrius Ružinskas
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Geomorphological Evidence of Ice Activity on Mars Surface at Mid-Latitudes

Remote Sensing
Extensive radar investigations, observed spectral signatures, geomorphological, and paleoclimate modeling support the presence of mid- to low-latitude ground ice on Mars. The presence of near-surface ice and glacial features has been proposed in Ismenius
Marco Moro, Adriano Nardi, Matteo Albano, Monica Pondrelli, Antonio Piersanti, Michele Saroli, Beatrice Baschetti, Erica Luzzi, Lucia Marinangeli, Nicola Bonora   +9 more
doaj   +1 more source

Theoretical Study on the Ice Melting with Transient Double Effects of Temperature and Concentration

Journal of Thermal Science and Technology, 2013
The melting of the ice plate with the transient double effects of the temperature and concentration was studied theoretically. In the present study, our main attention was paid to the early stage of melting, when the abrupt changes of the temperature and
Masahide NAKAMURA, Yoshimi KOMATSU, Yuuki KIMURA, Hirokuni HONGO, Orie TAMURA   +4 more
doaj   +1 more source

Ice Cold

Voices in Bioethics, 2014
While abhorrent by any standard, the Nazi medical experimentation has become a core illustration of unethically collected data currently being used in scientific research.1-4 Due to the extremes achieved – near-to sub-zero temperatures in investigating hypothermia and its effect on the body – some medical and scientific researchers have claimed it ...
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Is It Time for the Temple? [PDF]

, 2009
The current situation in Israel is one of constant tension and turmoil. Yet in the midst of Arab aggression and opposition, it appears that Jewish interest in rebuilding their Temple continues to grow.
Ice, Thomas D.
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

What is Replacement Theology? [PDF]

, 2009
Replacement theology “is the view that the church is the new or true Israel that has permanently replaced or superseded Israel as the people of God.”1 Another term, often found in academic circles, for replacement theology is supersessionism. Replacement
Ice, Thomas D.
core