Results 131 to 140 of about 1,124,625 (265)

Modulation of Biofunctional and Structural Properties in Stevia-Sweetened Ice Cream by Lactic Fermentation. [PDF]

Food Sci Nutr
Ozcan T, Keser G, Kaya AR, Cetin YE, Elciboga F.   +4 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Ice and Ecotrauma in Isaac Asimov’s “The Martian Way”

Fafnir
This article examines Isaac Asimov’s novella “The Martian Way” (1952) as a work that exposes the entanglements of the trauma of the environment with the ecological trauma of the humans.
Faeze Rezaii
doaj  

Ice ice maybe [PDF]

Nature Chemistry, 2010
openaire   +2 more sources

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Multidecadal preindustrial methane variability can be explained by noise in the source-sink imbalance. [PDF]

Proc Natl Acad Sci U S A
Mei EJ, Hakim GJ, Proistosescu C, Bauska TK, Buizert C, Turner AJ.   +5 more
europepmc   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Dimethylsulfoniopropionate metabolism shapes microbial ecology and physiological adaptation during the austral winter in Southern Ocean sea ice and seawater. [PDF]

Nat Commun
Buthelezi ZM, Pierneef RE, Bezuidt OKI, Gregori MNJ, Pesant S, Iudicone D, Hanwell L, Todd JD, Makhalanyane TP.   +8 more
europepmc   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Accuracy of a Deep Learning Model in Intracardiac Echocardiography. [PDF]

JACC Adv
Nair D, Winterfield J, Hsu JC, Gopinathannair R, Chinitz L, Pothineni NVK, Han FT, Dhakal BP, Barbhaiya C, Dave AS, Garcia F, Hyman MC, Dahlen T, Tanouye K, Yao J, Pawar S, Buckland J, Gilgur A, Elspas R, Gupta A, Sandler RA, Sokol JZ.   +21 more
europepmc   +1 more source