Results 91 to 100 of about 45,044 (305)
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Application of Extended Messinger Models to Complex Geometries [PDF]
Since, ice accretion can significantly degrade the performance and the stability of an airborne vehicle, it is imperative to be able to model it accurately.
Gupta, Avani +2 more
core +1 more source
Cooperative Origin of Low-Density Domains in Liquid Water
We study the size of clusters formed by water molecules possessing large enough tetrahedrality with respect to their nearest neighbors. Using Monte Carlo simulation of the SPC/E model of water, together with a geometric analysis based on Voronoi ...
C. A. Angell +10 more
core +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
LEWICE/E: An Euler based ice accretion code [PDF]
A new version of the LEWICE ice accretion computer code was developed which calculates the ice growth on two dimensional surfaces, incorporating the effects of compressibility through the solution of the Euler equations.
Potapczuk, Mark G.
core +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Marine icing is considered a major concern for vessels operating in the Arctic Ocean. Interaction between vessels and waves is the major source of sea spray that, under certain conditions, can lead to ice accretion on the vessels and thus create ...
Masoud Naseri, Eirik Mikal Samuelsen
doaj +1 more source
The UH-1H helicopter icing flight test program: An overview [PDF]
An ongoing joint NASA/Army program to study the effects of ice accretion on unprotected helicopter rotor aerodynamic performance is discussed. This program integrates flight testing, wind tunnel testing, and analytical modeling. Results are discussed for
Richter, G. P., Shaw, R. J.
core +1 more source
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Ice Accretion in Freezing Rain. [PDF]
Abstract : Ice accreted on structures from freezing rain causes both increased vertical loads and increased wind loads, due to the larger projected area of the structure. Structural failures initiated by ice loads frequently cause millions of dollars of damage to overhead power and communication lines, towers, and other ice-sensitive structures.
openaire +1 more source

