Results 61 to 70 of about 605,233 (331)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Report on limnological, biological and ecological observations of lakes on the Soya Coast, East Antarctica

Antarctic Record, 2008
Observations on the limnological properties, samplings of waters and bottom assemblages for biological and ecological studies, and some field experimental studies at several lakes in Soya Coast ice-free areas, were carried out during the austral summer ...
Sakae Kudoh, Yukiko Tanabe, Takahiro Iida, Megumu Tsujimoto, Mari Ogawa, Satoshi Imura   +5 more
doaj   +1 more source

Meteorological conditions in the central Arctic summer during the Arctic Summer Cloud Ocean Study (ASCOS) [PDF]

Atmospheric Chemistry and Physics, 2012
Understanding the rapidly changing climate in the Arctic is limited by a lack of understanding of underlying strong feedback mechanisms that are specific to the Arctic.
M. Tjernström, C. E. Birch, I. M. Brooks, M. D. Shupe, P. O. G. Persson, J. Sedlar, T. Mauritsen, C. Leck, J. Paatero, M. Szczodrak, C. R. Wheeler   +10 more
doaj   +1 more source

The Influence Between Ice Breaker And Learning Motivation Toward Learning Achievement Of Elementary School Social Science Subject

Proceedings of the International Conference Primary Education Research Pivotal Literature and Research UNNES 2018 (IC PEOPLE UNNES 2018), 2019
This study aims to examine the influence between ice breaker and learning motivation toward social science subject learning achievement. This study used correlational research design with quantitative approach. The sample of this study were 117 of fourth
E. Purwanti, Dianita Solihati, S. Sulistyorini, A. Busyairi   +3 more
semanticscholar   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Experimental Study on Preparation and Properties of New Paraffin Emulsion for Ice Slurry

Zhileng xuebao, 2017
A new kind of emulsion was prepared as a cold storage material for ice slurry using high-speed stirring and an ultra-sonication bath. Liquid paraffin and a compound of sodium oleate and cetyl trimethyl ammonium bromide (CTAB) were chosen as the oil phase
Yang Mingming, Sun Zhigao, Liu Minrui, Zhu Minggui, Wang Xiaochun, Li Cuimin, Li Juan, Huang Haifeng   +7 more
doaj  

The Arctic Council: transition of chairmanship from the US to Finland, further strengthening of Russian-Finnish cooperation [PDF]

Арктика и Север, 2017
The article deals with the results of the 2 years of the US chairmanship of the Arctic Council, notes positive results and draws attention to the weak points of the US Arctic policy.
Valeriy P. Zhuravel
doaj   +1 more source

THE USE OF ICE BREAKER TO IMPROVE STUDENTS’ MOTIVATION IN LEARNING ENGLISH AT THE TENTH GRADE STUDENTS OF SMK YPKKP

Project (Professional Journal of English Education), 2019
There is a belief that ice breaking can be used in the classroom as it provides several advantages for the students. One of them is that it can improve students’ learning motivation. This study aims to prove this belief.
Previa Rahmayanti, Putri Saraswati, G. P. Bhuana   +2 more
semanticscholar   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source