Results 41 to 50 of about 2,979,995 (245)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park +4 morewiley +1 more sourceAn epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz +14 morewiley +1 more sourceReconciliation of essential process parameters for an enhanced predictability of
Arctic stratospheric ozone loss and its climate interactions (RECONCILE): activities and results [PDF]
, 2013 The international research project RECONCILE has addressed central questions regarding polar ozone depletion, with the objective to quantify some of the most relevant yet still uncertain physical and chemical processes and thereby improve prognostic ...Khaykin, S. M., Wienhold, F G, F. G. Wienhold, Ebert, M., Molleker, S, Khosrawi, F., J. Kuttippurath, Ern, M., R. Kivi, Volk, C.M., Rognerud, B, Rolf, C, Santee, M.L., Suminska-Ebersoldt, O., M. von Hobe, Oelhaf, H., F. Stordal, Roeckmann, T., Woiwode, W., Kandler, K., I. Engel, Rolf, C., R. Lehmann, Hoyle, CR, Pope, F. D., Luo, B P, Günther, G., Stroh, F., Y. Orsolini, Hösen, E, Wienhold, FG, Lefèvre, Franck, G. Günther, Pitts, Mike C., Khaykin, SM, Hoyle, Christopher, von der Gathen, P, K. Kandler, S. Ludmann, Rognerud, B., M. Marchand, Stroh, F, Kivi, R, Khosrawi, F, Mitev, V., Von Der, Gathen P, Griessbach, S., M. Scheibe, Gulde, T, Riese, M., Scheibe, M, Weinbruch, S, Isaksen, Ivar S A, Walker, K, Ern, M, Siciliani de Cumis, M., Bekki, S, Spelten, N., Grooß, J-U, Peter, Thomas, Pitts, M C, von der Gathen, P., Stordal, F., J. Ungermann, Kivi, R., Viciani, S., Hösen, E., Laube, J.C., Santee, M L, F. Stroh, Ravegnani, F, Ebersoldt, A., N. Sitnikov, Kuttippurath, Jayanarayanan, Young, I., S. Bekki, Lehmann, Ralph, Yushkov, V., Marchand, M, Young, I. A. K., F. Lefèvre, H. Schlager, Olschewski, F., Isaksen, ISA, de Cumis, M. Siciliani, Jackson, D. R., Rognerud, Bjørg, Griessbach, S, Spang, R, Isaksen, I S A, Wetzel, G, Pope, F. D.; id_orcid, M. Ebert, Santee, M., Ludmann, S, T. Röckmann, Dörnbrack, A., Hoffmann, L, Marchand, M., A. Keil, Lefevre, F, Laube, J C, Ebersoldt, A, V. Yushkov, Wintel, J., Poole, L.R., Genco, S., K. Walker, Wohltmann, I, M. Rex, Wegner, T., Borrmann, Stephan, Ulanovski, A, von Hobe, M., Roiger, A, Santee, ML, Marchand, Marion, Jánosi, I., Wohltmann, I., Weinbruch, S., Stordal, F, von der Gathen, Peter, Olschewski, F, Lefèvre, F., S. Griessbach, Pope, F D, Viciani, S, Poole, L R, O. A. Søvde, F. D. Pope, Ungermann, J, Zobrist, B, W. Frey, Bekki, Slimane, Hoyle, C., Jackson, DR, Jánosi, IM, Hoffmann, L., I. Wohltmann, Wienhold, F., I. M. Jánosi, Søvde, O.A., Röckmann, T., Hoyle, C R, vom Scheidt, M., T. Peter, Khaykin, S., F. D'Amato, Di Donfrancesco, G, F. Cairo, Orsolini, Y, Riese, M. ., Emde, C, M. Siciliani de Cumis, Grooß, J.U., von Hobe, Marc, Luo, B.P., Engel, Ines, Frey, W., Jánosi, I. M., B. P. Luo, Young, I.A.K., Engel, I., Poole, LR, Jackson, D., Piesch, C., F. Ravegnani, Riese, M, Mueller, R., V. Homonnai, Jackson, D.R., Poole, Lamont R., Doernbrack, A., Peter, T., Rex, Markus, Mitev, Valentin, C. Piesch, Søvde, O A, Jackson, D R, Jones, R. L., Yushkov, V, J.-U. Grooß, Rex, M, M. Riese, J. C. Laube, Young, IAK, Roiger, Anke, A. Ebersoldt, Weigel, R., Kalicinsky, C., Jánosi, I M, C. Kalicinsky, Sumińska-Ebersoldt, O, Schiller, C., Rockmann, T, H. Oelhaf, Peter, T, Keil, A., Gulde, T., R. Müller, T. Gulde, Luo, B. P., Søvde, OA, Sitnikov, N., Borrmann, S, Cairo, F., Grooß, J.-U., Kalicinsky, C, Ebert, M, Spang, R., Pitts, MC, Scheibe, M., Pope, F.D., I. A. K. Young, F. Olschewski, Schlager, H, Meyer, J., Santee, M. L., Khaykin, Sergey, Hoyle, Christopher R., Scheibe, Monika, Kuttippurath, J, Poole, L., Mitev, V, Ravegnan, F., S. Molleker, Rex, M., Jones, R., Søvde, O., Zobrist, Bernhard, Weigel, R, Wetzel, G., A. Roiger, Pitts, M., C. Schiller, B. Zobrist, O. Sumińska-Ebersoldt, R. L. Jones, S. Weinbruch, Homonnai, V, Isaksen, I., Hoyle, C.R., Laube, JC, Volk, CM, Roiger, A., Jánosi, I.M., Oelhaf, H, S. Borrmann, J. Meyer, Orsolini, Y., Pfeilsticker, K, Jones, R.L., L. Hoffmann, Young, I A K, Ulanovski, A., C. Emde, Wienhold, F.G., Bekki, S., Luo, Beiping P., Jones, RL, N. Spelten, Laube, J., Guenther, G., S. Genco, Jones, R L, D'Amato, F., G. Wetzel, Borrmann, S., Hoesen, E., Volk, C., V. Mitev, Spelten, N, Wegner, T, Ravegnani, F., Weinbuch, S., Poole, L. R., Engel, I, Pope, FD, Lehmann, R., Orsolini, Yvan, Grooß, J., Volk, C M, Schlager, Hans, Siciliani, De Cumis M, Stordal, Frode, Kandler, K, G. Di Donfrancesco, A. Dörnbrack, Isaksen, I. S. A, Frey, W, C. R. Hoyle, M. L. Santee, Emde, Claudia, Pope, F., E. Hösen, Kuttippurath, J., Emde, C., Pfeilsticker, K., Dörnbrack, Andreas, Grooss, J. -U., A. Ulanovski, Müller, R, Dörnbrack, A, P. von der Gathen, Schiller, C, Isaksen, I.S.A., Luo, BP, Isaksen, I. S. A., Scheidt, M., Pitts, M. C., S. M. Khaykin, Sitnikov, N, Ern, Manfred, Søvde, O. A., D. R. Jackson, Khaykin, S.M., Siciliani de Cumis, M, Ungermann, J., Meyer, J, von Hobe, M, Søvde, Ole Amund, Khaykin, S M, Lehmann, R, T. Wegner, Pitts, M.C., S. Viciani, Luo, B., I. S. A. Isaksen, M. vom Scheidt, Vom, Scheidt M, Müller, R., Woiwode, W, Schlager, H., vom Scheidt, M, Wohltmann, Ingo, K. Pfeilsticker, Piesch, C, Wienhold, Frank G., Di Donfrancesco, G., C. M. Volk, Keil, A, R. Spang, D'Amato, F, Walker, K., M. Ern, Homonnai, V., B. Rognerud, Laube, J. C., C. Rolf, F. Khosrawi, Genco, S, R. Weigel, Hoyle, C. R., M. C. Pitts, W. Woiwode, Wienhold, F. G., Volk, C. M., Günther, G, Sovde, O. A., Griessbach, Sabine, L. R. Poole, Ludmann, S., Cairo, F, Molleker, S., Zobrist, B., Kuttippurath, Jayan, Marine and Atmospheric Research, Wienhold, Franck G., Yushkov, Vladimir, Hoffmann, Lars, Kivi, Rigel, Doernbrack, A, Weigel, Ralf, Young, Isla A. K., Grooß, Jens-Uwe, Günther, Gebhard, Riese, Martin, Müller, Rolf, Molleker, Sergej, vom Scheidt, Marcel, Pope, Francis D., Sitnikov, Nikolay, Oelhaf, Hermann, Sumińska-Ebersoldt, Olga, Stroh, Fred, Hobe, Marc von, D'Amato, Francesco, Sub Atmospheric physics and chemistry, Cairo, Francesco, Kandler, Konrad, Hoyle, Christopher Robert, Meyer, Jessica, Rolf, Christian, Siciliani de Cumis, Matteo, et al., [No Value], Hösen, Elisabeth, Olschewski, Friedhelm, Frey, Wiebke, Walker, Kaley A., Röckmann, Thomas, Spelten, Nicole, Isaksen, Ivar S.A., Homonnai, Viktoria, Spang, Reinhold, Viciani, Silvia, Ravegnani, Fabrizio, Khosrawi, Farahnaz,, Santee, Michelle L., Piesch, Christof, Ludmann, Sabrina, Weinbruch, Stephan, Grissbach, S, Di Donfrancesco, Guido, Ebersoldt, Andreas, Ulanovski, Alexey, Ebert, Martin, Pfeilsticker, Klaus, Guenther, G, Wetzel, Gerald, Schiller, Cornelius, Wegner, Tobias, et, al., Gathen, Peter von der, Pitts, Michael C., Genco, Silvia, Khaykin, Sergey M., Kalicinsky, Christoph, Jones, Rod L., Hoesen, E, Khosrawi, Farahnaz, Gulde, Thomas, Laube, Johannes Christian, Jackson, David R., Volk, C.-Michael, Woiwode, Wolfgang, Jánosi, Imre M., Keil, Andrea +436 morecore +3 more sourcesPreindustrial to present-day changes in tropospheric hydroxyl radical and methane lifetime from the Atmospheric Chemistry and Climate Model Intercomparison Project (ACCMIP) [PDF]
, 2013 We have analysed time-slice simulations from 17 global models, participating in the Atmospheric Chemistry and Climate Model Intercomparison Project (ACCMIP), to explore changes in present-day (2000) hydroxyl radical (OH) concentration and methane (CH4 ...Rumbold, S, Sudo, K., Faluvegi, G., Nagashima, T, Shindell, Drew T., Young, Paul, MacKenzie, Ian A., Fiore, Arlene M., Voulgarakis, A., Eyring, V., Cameron-Smith, Philip, Lamarque, Jean-Francois, Lin, M, Prather, Michael J., Dalsoren, Stig B, Josse, B, Stevenson, D. S., Bergmann, Daniel, Doherty, R. M., Strode, Sarah, Folberth, G., Righi, M, Horowitz, L. W., Szopa, Sophie, Naik, Vaishali, Collins, William J., Lee, Yunha H, Zeng, Guang, van Noije, T. P. C., Cionni, I, Plummer, David A, Skeie, R +31 morecore +3 more sourcesNutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal +4 morewiley +1 more sourcePeripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini +8 morewiley +1 more sourceDo atmospheric aerosols form glasses? [PDF]
, 2008 Zobrist B, Marcolli C, Pedernera DA, Koop T. Do atmospheric aerosols form glasses? ATMOSPHERIC CHEMISTRY AND PHYSICS. 2008;8(17):5221-5244.A new process is presented by which water soluble organics might influence ice nucleation, ice growth, chemical ...Koop, Thomas, B. Zobrist, D. A. Pedernera, Koop, T., Koop, Thomas ; https://orcid.org/, Pedernera, D. A., Marcolli, C., C. Marcolli, T. Koop, Marcolli, Claudia, Pedernera, D.A., Zobrist, Bernhard, Zobrist, B. +12 morecore +2 more sourcesGolgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.Dominik P. Buser, Tina Junnewiley +1 more source