Results 61 to 70 of about 2,979,995 (245)

Annotated bibliography of the Russian languages literature on glaciology for 2015

Лëд и снег, 2017
The proposed annual bibliography continues annotated lists of the Russian‑language literature on glaciology that were regularly published in the past. It includes 245 references grouped into the following ten sections: 1)  general issues of glaciology; 2)
V. M. Kotlyakov, L. P. Chernova
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

ANNOTATED BIBLIOGRAPHY OF THE RUSSIAN LANGUAGES LITERATURE ON GLACIOLOGY FOR 2016

Лëд и снег, 2018
The proposed annual bibliography continues annotated lists of the Russian‑language literature on glaciology that were regularly published in the past. It includes 345 references grouped into the following ten sections: 1)  general issues of glaciology; 2)
V. M. Kotlyakov, L. P. Chernova
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Chlorine peroxide reaction explains observed wintertime hydrogen chloride in the Antarctic vortex

Communications Earth & Environment
It is well established that the drastic ozone loss in the Antarctic stratosphere, commonly known as the ozone hole, is primarily driven by gas-phase and heterogeneous chemical processes. While chemistry transport models generally reproduce observed ozone
Jens-Uwe Grooß, Rolf Müller, John N. Crowley, Michaela I. Hegglin   +3 more
doaj   +1 more source

The response of Antarctic sea ice algae to changes in pH and CO2.

PLoS ONE, 2014
Ocean acidification substantially alters ocean carbon chemistry and hence pH but the effects on sea ice formation and the CO2 concentration in the enclosed brine channels are unknown.
Andrew McMinn, Marius N Müller, Andrew Martin, Ken G Ryan   +3 more
doaj   +1 more source

Annotated bibliography of the Russian literature on glaciology for 2014

Лëд и снег, 2016
The proposed annual bibliography continues annotated lists of the Russian-language literature on glaciology that were regularly published in the past. It includes 271 references grouped into the following ten sections: 1) general issues of glaciology; 2)
V. M. Kotlyakov, L. P. Chernova
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Molecular investigations of atmospherically relevant interface processes: ice formation and water accommodation on ice and organic surfaces [PDF]

, 2014
Clouds and aerosols play important roles in the climate system by affecting on atmospheric chemistry, the radiation budget of the atmosphere, and the water cycle including the formation of precipitation.
Kong, Xiangrui
core   +1 more source