Results 141 to 150 of about 1,498,627 (306)
FEBS Open Bio, EarlyView.NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Spatial cross-correlation of Antarctic Sea ice and seabed topography [PDF]
A time series of derived sea ice concentrations as observed about Antarctica by the Nimbus-7 Scanning Multichannel Microwave Radiometer (SMMR) satellite in 1983 is considered.
Deveaux, Richard D., Phelan, Michael J.
core +1 more source
GEOGRAPHICAL DIFFERENCES IN CONCENTRATIONS OF ICE NUCLEI
Monthly Weather Review, 1964 Abstract On the basis of mixing chamber measurements of the concentrations of ice nuclei at Mauna Lao it is suggested that Kline's conclusion that the counts were conspicuously lower than elsewhere, may have been instrumental in origin.
openaire +1 more source
FEBS Open Bio, EarlyView.We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley +1 more source
Lidar and aircraft studies of deep Cirrus systems from the 1986 FIRE IFO [PDF]
Several NCAR King Air flight missions were conducted during the Wisconsin FIRE IFO experiment in support of the University of Utah polarization lidar observations of deep cirrus cloud systems at the Wausau ground site.
Heymsfield, Andrew J. +2 more
core +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Satellite-derived ice data sets no. 2: Arctic monthly average microwave brightness temperatures and sea ice concentrations, 1973-1976 [PDF]
A summary data set for four years (mid 70's) of Arctic sea ice conditions is available on magnetic tape. The data include monthly and yearly averaged Nimbus 5 electrically scanning microwave radiometer (ESMR) brightness temperatures, an ice concentration
Comiso, J. C. +2 more
core +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Sea ice - atmosphere interaction: Application of multispectral satellite data in polar surface energy flux estimates [PDF]
In the past six months, work has continued on energy flux sensitivity studies, ice surface temperature retrievals, corrections to Advanced Very High Resolution Radiometer (AVHRR) thermal infrared data, modelling of cloud fraction retrievals, and ...
Haefliger, M. +5 more
core +1 more source