Results 121 to 130 of about 1,498,627 (306)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Concentrated Loads on a Floating Ice Sheet [PDF]
Journal of Glaciology, 1977 AbstractThe safe bearing capacity of a floating ice sheet is usually determined by limiting the maximum tensile stress which occurs under the load at the bottom of the ice sheet. If the size of the load distribution is large compared to the ice thickness, the thin plate theory predicts these stresses correctly.
openaire +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Chemical species spatial distribution and relationship to elevation and snow accumulation rate over the Greenland Ice Sheet [PDF]
, 1996 Major chemical species (Cl−, NO−3, SO2−4, Na+, K+, Mg2+, Ca2+) from 24 snowpits (sampled at a resolution of 3 cm, total 2995 samples) collected from northern, central, and southern Greenland were used for this investigation.
Linder, E. +4 more
core +3 more sources
Ice concentration measurement and control for ice slurry flow
, 2006 Ice concentration must be accurately known for most experimental researches about ice slurry and its selected value must be maintained steady during test time to assure the validity of the results obtained. The aim of this work is to present the practical solutions adopted in an experimental study to achieve the two above cited requirements in a wide ...
Illán Gómez, Fernando +1 more
openaire +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
E3S Web of Conferences, 2018 Ice slurry technology has great potential in maximizing the chilling process of fish. Seawater is widely used as base solution of ice slurry due to Natrium Chloride content as freezing point depressant.
Rayhan Fajri A, Yanuar, Pamitran Agus S
doaj +1 more source
Technical note: formation of airborne ice crystals in a wall independent reactor (WIR) under atmospheric conditions [PDF]
, 2008 Both, gas and particle scavenging contribute to the transport of organic compounds by ice crystals in the troposphere. To simulate these processes an experimental setup was developed to form airborne ice crystals under atmospheric conditions. Experiments
Fries, Elke +6 more
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source