Results 151 to 160 of about 3,287,043 (305)

(Figure 3) Dust concentration measurements in RECAP ice core, Holocene

, 2019
(Figure 3) Dust concentration measurements in RECAP ice core ...
Grinsted, Aslak, Mai Winstrup (7698524), Gisela Winckler (6975875), Robert Frei (7698515), Simonsen, Marius Folden, Marius Folden Simonsen (7698503), Paul T Vallelonga (6961475), Frei, Robert, Blunier, Thomas, Delmonte, Barbara, Steven L Goldstein (6965516), Goldstein, Steven L, Kjær, Helle Astrid, Todd A Sowers (6967661), Baccolo, Giovanni, Diana Vladimirova (2882153), Bo M Vinther (6972494), Vallelonga, Paul T, Vladimirova, Diana, Giovanni Baccolo (6978047), Winckler, Gisela, Vinther, Bo Møllesøe, Alejandra Borunda (7698509), Sowers, Todd A, Anders M Svensson (6968876), Borunda, Alejandra, Barbara Delmonte (7698512), Winstrup, Mai, Helle Astrid Kjær (7698521), Aslak Grinsted (7698518), Svensson, Anders M, Thomas Blunier (7698506)   +31 more
core   +1 more source

In‐House Manufacturing of 3D ECM Culture Chips via Vacuum Thermoforming for Enhanced Imaging Applications

Advanced Materials Technologies, EarlyView.
Desktop vacuum thermoforming enables rapid, low‐cost fabrication of 96‐channel polystyrene culture chips with very thin imaging interfaces. The resulting platform supports cell lines, primary cells, and patient‐derived organoids, and enables high‐resolution confocal microscopy and single‐cell visualization, providing an accessible approach for advanced
Aleksandra Fomina, Adam Tam, Jennifer Lam, Nila C. Wu, Nancy T. Li, Alison P. McGuigan   +5 more
wiley   +1 more source

Multiobjective Codesign Optimization of a Planar Pneumatic Artificial Muscle‐Based Snake‐Like Robot for Enhanced Agility and Energy Efficiency

Advanced Robotics Research, EarlyView.
A codesign multiobjective optimization framework was developed to enhance the morphology and controller of a snake‐like robot driven by artificial muscles. It improved planar locomotion, agility, and power efficiency. The approach optimized link geometry and controller gains, revealing that shorter muscles near joints and longer linkages maximize ...
Ayla Valles, Mahdi Haghshenas‐Jaryani
wiley   +1 more source

A 120,000-year long climate record from a NW-Greenland deep ice core at ultra-high resolution. [PDF]

Sci Data, 2021
Gkinis V, Vinther BM, Popp TJ, Quistgaard T, Faber AK, Holme CT, Jensen CM, Lanzky M, Lütt AM, Mandrakis V, Ørum NO, Pedersen AS, Vaxevani N, Weng Y, Capron E, Dahl-Jensen D, Hörhold M, Jones TR, Jouzel J, Landais A, Masson-Delmotte V, Oerter H, Rasmussen SO, Steen-Larsen HC, Steffensen JP, Sveinbjörnsdóttir ÁE, Svensson A, Vaughn B, White JWC.   +28 more
europepmc   +1 more source

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

Advanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García, Kerry R. McGreevy, Maria Eugenia Vaquero, Juan M. Suarez‐Rivero, Antonio Moreno‐Rodríguez, Antonio J. Pérez‐Pulido, Daniel Ramírez de Mingo, Anna Pallé, Helena Akiko Popiel, Andrea Santi, Mario D. Cordero, José Luis Trejo, Yoshitaka Nagai, Mariano Carrión‐Vázquez   +13 more
wiley   +1 more source

Iron in the NEEM ice core relative to Asian loess records over the last glacial-interglacial cycle. [PDF]

Natl Sci Rev, 2021
Xiao C, Du Z, Handley MJ, Mayewski PA, Cao J, Schüpbach S, Zhang T, Petit JR, Li C, Han Y, Li Y, Ren J.   +11 more
europepmc   +1 more source

Core of ice [PDF]

Nature Geoscience, 2010
openaire   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

Advanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang, Hongyu Zhu, Wenqi Wang, Bingqian Shen, Yuanyuan Xin, Xingxing Song, Xuanyi Lu, Lixuan Li, Siting Chen, Xiaochen Zhang, Jialing Zeng, Haodong Zheng, Jianlong Lao, Ke Peng, Yixian Wei, Jiaming Zheng, Chuanhuo Hu, Xiaoye Wang, Xun Li   +18 more
wiley   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source