Results 131 to 140 of about 2,872,579 (294)

Revised historical Northern Hemisphere black carbon emissions based on inverse modeling of ice core records. [PDF]

open access: yesNat Commun, 2023
Eckhardt S   +15 more
europepmc   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao   +10 more
wiley   +1 more source

Use of δ18Oatm in dating a Tibetan ice core record of Holocene/Late Glacial climate. [PDF]

open access: yesProc Natl Acad Sci U S A, 2022
Thompson LG   +7 more
europepmc   +1 more source

On ice cores chronologies

open access: yes
Polar ice in Antarctica and Greenland is a primary archive to reconstruct Quaternary climate. An accurate chronology is necessary to exploit this archive. Dating methods can be derived from the counting of annual layers, from radioactive methods, from the comparison to other archives or from the modelling of the glacial sedimentation process.
Parrenin, Frédéric, Landais, Amaelle
openaire   +2 more sources

Ice Core Facility

open access: yesEos, Transactions American Geophysical Union, 1990
To support its program of studying ice cores taken from the Greenland, Antarctic and midlatitude ice sheets, the Division of Polar Programs of the National Science Foundation is soliciting proposals for operating its ice core curatorial facility.NSF's current ice core repository is at the State University of New York at Buffalo, where it has been ...
openaire   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

open access: yesAdvanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li   +9 more
wiley   +1 more source

Ice core evidence for atmospheric oxygen decline since the Mid-Pleistocene transition. [PDF]

open access: yesSci Adv, 2021
Yan Y   +4 more
europepmc   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

open access: yesAdvanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song   +14 more
wiley   +1 more source

Geochemical ice-core constraints on the timing and climatic impact of Aniakchak II (1628 BCE) and Thera (Minoan) volcanic eruptions. [PDF]

open access: yesPNAS Nexus, 2022
Pearson C   +9 more
europepmc   +1 more source

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

open access: yesAdvanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh   +11 more
wiley   +1 more source

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