Results 131 to 140 of about 815,112 (296)

Programmable Microgel Degradation in Dynamic Granular Hydrogels Guides Extracellular Matrix Assembly During Tissue Repair

open access: yesAdvanced Materials, EarlyView.
This study reports on the chemical modification of hyaluronic acid to create hydrogels with hydrolytic degradability ranging from 2–28 days. Granular hydrogels that undergo timed degradation to increase porosity enhance cell invasion and provisional ECM remodeling in a muscle injury model, leading to reduced fibrosis and improved regeneration ...
Zhiyuan Chen   +7 more
wiley   +1 more source

Consistent dating for Antarctic and Greenland ice cores

open access: yes, 2010
International audienceWe are hereby presenting a new dating method based on inverse techniques, which aims at calculating consistent gas and ice chronologies for several ice cores.
Blayo, Eric   +19 more
core   +1 more source

Formation scenarios of dense starless cores from their ice composition

open access: yesAstronomy & Astrophysics
Context. Dense, dark, starless cores of molecular clouds form in large-scale processes. The evolution of physical conditions in forming dense cores is often regulated by external phenomena and cannot be easily reproduced with models considering only the ...
Kalvāns Juris
doaj   +1 more source

A Noninvasive Approach to Study Localized Forces in 3D Epithelia

open access: yesAdvanced Materials, EarlyView.
Epithelial morphogenesis depends on dynamic mechanical coupling between adhesion complexes and the cytoskeleton, yet its regulation in polarized 3D tissues remains elusive. We developed a noninvasive strategy using cell‐like elastic microbeads to quantify local forces in intact epithelia.
Niels Gouirand   +9 more
wiley   +1 more source

Defined Matrices Reveal Epithelial‐ and Mesenchymal‐Specific Responses to Stiffness and Adhesion in Human iPSC‐Derived Intestinal Organoids

open access: yesAdvanced Materials, EarlyView.
Defined PEG hydrogels enable human iPSC‐derived intestinal organoid culture without Matrigel. PEG‐ and Matrigel‐cultured organoids both support duodenal‐like epithelial identity, but direct comparison reveals subtle epithelial differentiation‐marker shifts and stronger mesenchymal ECM‐remodeling/integrin programs in PEG.
Alicja Kuziola   +8 more
wiley   +1 more source

H4F talk with Dania Achermann: Ice cores, small states and global climate change

open access: yes, 2021
For our final talk of the series H4F chat with Dania Achermann the topic “Histories of Climate Science”. We talk about Dania’s research on ice-core paleoclimatology and the cultural-political factors that shape how we know and understand climate sciences.
Achermann, Dania
core  

An Engineered Thio‐Amino Polymer Achieves Potent, Safe, and Broad Cell Type Delivery in the Lung Mapped by Spatial Transcriptomics

open access: yesAdvanced Materials, EarlyView.
Synthesis and screening of a polymer library produced a versatile and inhalable mRNA vehicle for the lungs (P81). Compared to a published LNP, P81 provides increased delivery efficacy, achieving widespread expression in broad cell types, with no toxicity.
Pramodkumar EK   +36 more
wiley   +1 more source

Bilayered PEDOT:PSS–Collagen Scaffolds as Functional Architectures for Tissue Engineering

open access: yesAdvanced Materials Interfaces, EarlyView.
A bilayered scaffold integrates collagen and PEDOT:PSS as distinct yet interconnected 3D matrices, preserving their fibrillar and conductive characteristics. Spatial compartmentalization enables independent tailoring of each domain while maintaining mechanical stability and compatibility with electrochemical monitoring, providing a multifunctional ...
Rasha Nasser   +6 more
wiley   +1 more source

Bromine Enrichment Signal in Svalbard Shallow Cores Reflects Changes of Seasonal Sea Ice Variability

open access: yesGeophysical Research Letters
Bromine enrichment Brenr has been widely used as a proxy for past sea ice reconstructions. In this study, three firn cores drilled on Holtedahlfonna (Svalbard) were analyzed for trace elements.
Enrico Biscaro   +13 more
doaj   +1 more source

Control of Bacterial Attachment on Macroporous PDMS/Paraffin SLIPS With Varying Lubricant Viscosity

open access: yesAdvanced Materials Interfaces, EarlyView.
Slippery liquid‐infused porous surfaces (SLIPS) prepared from macroporous PDMS, infused with medical‐grade paraffins, were systematically investigated regarding the correlation of viscosity, surface corrugation, bulk porosity, and bacterial resistance. Substrate porosity was found to dominate lubricant stabilization and the antifouling activity.
Regina Kopecz   +3 more
wiley   +1 more source

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