Results 171 to 180 of about 3,234 (297)

Multiobjective Codesign Optimization of a Planar Pneumatic Artificial Muscle‐Based Snake‐Like Robot for Enhanced Agility and Energy Efficiency

Advanced Robotics Research, EarlyView.
A codesign multiobjective optimization framework was developed to enhance the morphology and controller of a snake‐like robot driven by artificial muscles. It improved planar locomotion, agility, and power efficiency. The approach optimized link geometry and controller gains, revealing that shorter muscles near joints and longer linkages maximize ...
Ayla Valles, Mahdi Haghshenas‐Jaryani
wiley   +1 more source

A glimpse into the future: How the timing of sea ice formation influences associated microalgal communities. [PDF]

iScience
Stuart J, Robinson N, Stewart C, Smith KF, Pearman JK, Halfter S, Leonard G, Ryan KG.   +7 more
europepmc   +1 more source

3D Printing of Soft Robotic Systems: Advances in Fabrication Strategies and Future Trends

Advanced Robotics Research, EarlyView.
Collectively, this review systematically examines 3D‐printed soft robotics, encompassing material selections, function integration, and manufacturing methodologies. Meanwhile, fabrication strategies are analyzed in order of increasing complexity, highlighting persistent challenges with proposed solutions.
Changjiang Liu, Bin Cui, Xumin Huang, Xiaoyu (Rayne) Zheng, T. Thang Vo‐Doan, Ruirui Qiao   +5 more
wiley   +1 more source

High-resolution forest and fire dynamics from Fish Lake, New Brunswick, Canada, during the last millennium. [PDF]

Holocene
Collins RJ, St-Jacques JM, Kyle KA, Cwynar LC, Cogbill CV.   +4 more
europepmc   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

Southern Ocean seabird population shifts over the Holocene revealed by peat sequestration of mercury from guano. [PDF]

Proc Natl Acad Sci U S A
Li C, Roberts SJ, Grosjean M, Mestrot A, Wille M, Phillips RA, Enrico M, Bishop K, Skyllberg U, Mauquoy D, von Scheffer C, Theurer T, Muirhead D, Whittle A, Gallego-Sala A, Sonke JE, De Vleeschouwer F, Van der Putten N, Braconnot P, Marti O, Osterwalder S, Buchmann N, Frölicher T, Anthamatten E, Chiaia-Hernández AC, Zahajská P, Jeandel C, Saunders KM, Kwon SY, Wang D, Bindler R, Sime L, Hodgson DA.   +32 more
europepmc   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

Field data on sea ice restoration by artificial flooding. [PDF]

Data Brief
Hammer TC, Shestov A, van Dijke LL, Ypma F, Meijeraan T, Hendrikse H.   +5 more
europepmc   +1 more source

Ice coring and drilling technologies developed by the Polar Ice Coring Office

Ice coring and drilling technologies developed by the Polar Ice Coring Office
P(論文) The search for "zero defects" ice cores continues to challenge the ice coring and drilling community. No single drilling and coring device will fill all needs. Each project will have special requirements and will require an initial decision as to the most effective drilling system to be used as well as ensuring personal and environmental safety ...
openaire  

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source