Results 191 to 200 of about 562,841 (289)

MZF1 Inhibits TGFβ‐1/SMAD Signaling by Transcriptionally Activating SnoN to Augment Tumorigenic Potential in Colon Cancer

Advanced Science, EarlyView.
This study identifies MZF1 as a core regulator of colon cancer via SnoN‐mediated TGF‐β suppression, proposes 10Panx Acetate as a targeted inhibitor, and validates MZF1/SnoN as prognostic markers for aggressive disease. ABSTRACT Colon cancer progression is associated with transcriptional and signaling abnormalities.
Siqi Sheng, Mengxi Huang, Yiting Wang, Hongyu Wang, Haimei Feng, Xiaoming Bai, Jie Chen, Ke Xu, Xiaoyuan Chu, Zengjie Lei   +9 more
wiley   +1 more source

Repeated loss of the West Antarctic Ice Sheet's Amundsen Sea sector during late Pleistocene interglacials. [PDF]

Nat Commun
Hillenbrand CD, Ehrmann W, Park YK, Kim J, Bohaty SM, Scherer RP, Ruggiero JA, Wellner JS, Gohl K, Totten RL, Larter RD, Esteves M, Klages JP, Smith JA, Frederichs T, Horikawa K, Passchier S, Mastro JR, Bauersachs T, Hopkins BA, Xuan C, Ó Cofaigh C, Clark RW, Marschalek JW, Simões Pereira P, Reinardy BTI, Halberstadt ARW, Wu L, Cowan EA, Siddoway CS, Robinson DE, Iwai M, Gao L, Hemming SR, Penkrot ML, King TM, Lloyd JM, Kulhanek DK.   +37 more
europepmc   +1 more source

Ice Core Walk

, 2020
Philippe Tortell, Chris Chafe, Greg Niemeyer   +2 more
openaire   +1 more source

Atmospheric Water Harvesting Through Polymer Hydrogel Sorbents: Materials Chemistry, Design Strategies, and Applications

Advanced Science, EarlyView.
Polymer‐based hydrogels have emerged as promising materials for atmospheric water harvesting (AWH) due to their high water affinity, tunable network structure, and excellent moisture adsorption‐desorption performance. Functional hydrogel systems enable efficient water capture and controlled release under low‐energy conditions, offering a sustainable ...
Swagata Datta, Sushmit Sen, Nilanjan Dey, Amrita Chatterjee, Ananya Sadhu, Sudipta Sarkar, Pradip K. Maji   +6 more
wiley   +1 more source

High-resolution forest and fire dynamics from Fish Lake, New Brunswick, Canada, during the last millennium. [PDF]

Holocene
Collins RJ, St-Jacques JM, Kyle KA, Cwynar LC, Cogbill CV.   +4 more
europepmc   +1 more source

Additive Manufacturing of High‐Performance Polymers for Extreme Environments

Advanced Science, EarlyView.
Additive manufacturing of high‐performance polymers for extreme environments is critically reviewed through an integrated chemistry‐processing‐structure‐property‐qualification framework. The review compares fused filament fabrication, selective laser sintering, and direct ink writing, linking rheology and thermal history to crystallization, defect ...
Md Tofazzal Hossain, Mohammed Intishar Nur, Md Shajedul Hoque Thakur, Indranil Dey, Md Mesbahul Maruf, Md Jahid Hasan, Suryasarathi Bose, Muhammad M. Rahman   +7 more
wiley   +1 more source

Field data on sea ice restoration by artificial flooding. [PDF]

Data Brief
Hammer TC, Shestov A, van Dijke LL, Ypma F, Meijeraan T, Hendrikse H.   +5 more
europepmc   +1 more source

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

Advanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke, Xin Li, Xiaoli Wang, Zhaoxia Huang, Shaojie Xue, Yuyang Liu, Jing Pan, Guowei Hu, Yayu Wang, Cheng Wang, Shoudeng Chen   +10 more
wiley   +1 more source

Joint Inversion of Radionuclide Production Rate Data and Thermoremanent Magnetic Records over the Holocene. [PDF]

Sol Phys
Schanner MA, Nilsson A, Muscheler R.
europepmc   +1 more source

Thermochemical Core–Shell Architecturing of Si‐SWCNT Composites for High‐Performance Li‐Ion Battery Anodes

Advanced Science, EarlyView.
A thermochemically engineered core–shell Si architecture is developed through the controlled evolution of a SWCNT‐coated Mg2Si precursor. The process simultaneously generates a nanoporous Si shell for strain accommodation and Li+ transport, a chemically anchored SiC interfacial layer for robust mechanical and electrical coupling, and a Mg‐containing Si
Dong Gyun Hong, Byeong Guk Kim, Jung‐Hyeok Park, Sunwoo Lee, Donghwi Cho, Jaeik Hyun, Ki‐Hun Nam, Youngoh Kim, Geon‐Woong Lee, Sunhye Yang, Seung Yol Jeong, Myungwoo Choi   +11 more
wiley   +1 more source