Results 211 to 220 of about 3,090,231 (345)

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

An analytical study for predicting incipient motion velocity of sediments under ice cover. [PDF]

Sci Rep
Luo H, Ji H, Chen Z, Liu B, Xue Z, Li Z.
europepmc   +1 more source

Variations in Atlantic water influx and sea-ice cover drive taxonomic and functional shifts in Arctic marine bacterial communities

, 2022
Priest T, Appen Wv, Oldenburg E, Popa O, Torres-Valdés S, Bienhold C, Metfies K, Fuchs BM, Amann R, Boetius A, Wietz M.   +10 more
europepmc   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Ice and Icebergs

, 2011
The Freeze Frame website presents an online catalogue of over 20,000 images from the historic negative collections at the Scott Polar Research Institute.
Heather Lane, Scott Polar Research Institute, University of Cambridge   +2 more
core  

Lessened projections of Arctic warming and wetting after correcting for model errors in global warming and sea ice cover. [PDF]

Sci Adv
Cai Z, You Q, Screen JA, Chen HW, Zhang R, Zuo Z, Chen D, Cohen J, Kang S, Zhang R.   +9 more
europepmc   +1 more source

Antarctic food web architecture under varying dynamics of sea ice cover. [PDF]

Sci Rep, 2019
Rossi L, Sporta Caputi S, Calizza E, Careddu G, Oliverio M, Schiaparelli S, Costantini ML.   +6 more
europepmc   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Group 2i Isochrysidales thrive in marine and lacustrine systems with ice cover. [PDF]

Sci Rep
Wang KJ, Huang Y, Kartzinel T, Majaneva M, Richter N, Liao S, Andresen CS, Vermassen F.   +7 more
europepmc   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source