Results 171 to 180 of about 17,539 (262)

Extracellular vesicles released from melanoma cells constitutively expressing MHC class II promote immune evasion and cancer progression

The FEBS Journal, EarlyView.
Here, we report the role of extracellular vesicles (EVs) released from melanoma cells constitutively expressing MHC class II in the regulation of immune cell functions and melanoma metastasis. In particular, we observed an increased localization of HLA‐DRα, CAM receptors, PD‐L1, and STAT3 signaling proteins in the EVs.
Francesca Costantini, Caterina Di Sano, Samuele Raccosta, Mauro Manno, Giovanna Barbieri   +4 more
wiley   +1 more source

Recurrent DNA break clusters drive replication-stress-induced copy number variants and genome diversification. [PDF]

Nat Commun
Corazzi L, Ing A, Benito E, Cosenza MR, Hasenfeld P, Weber T, Marx AJM, Ionasz VS, Trausch N, Benedetto S, Di Muzio G, Ding B, Berlanda J, Giaisi M, Claudino N, Höfer T, Korbel JO, Wei PC.   +17 more
europepmc   +1 more source

Anemia‐associated mutations disrupt the CDIN1‐Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA‐I) disease

The FEBS Journal, EarlyView.
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal, Tomas Brom, Ivona Nečasová, Tomáš Janovič, Pavel Veverka, Naina Verma, Lukáš Uhrík, Lenka Hernychova, Ctirad Hofr   +8 more
wiley   +1 more source

Voltage-dependent G-protein regulation of Ca_V2.2 (N-type) channels. [PDF]

Sci Adv
Nilsson M, Wang K, Mínguez-Viñas T, Angelini M, Berglund S, Olcese R, Pantazis A.   +6 more
europepmc   +1 more source

SN 1054, SN 1006, & Nova WZ Sagittae Calving Antarctic Ice Cap—Global Warming & Moose Die Off Longitude Relationship Deflection Area in Antarctica and USA—WZ Sagittae Impact and Martian Dust Storms [PDF]

Journal of Earth Science and Engineering, 2018
openaire   +1 more source

Potential of organogel‐based colloidal hydrogels for new cosmetic formulations

International Journal of Cosmetic Science, EarlyView.
Colloidal hydrogels are formed by combining anionic, cationic, or nonionic surfactants with two oils of cosmetic interest: sweet almond oil and phytosqualane. These systems are obtained through hot emulsification followed by cooling, which leads to the aggregation of gel‐like particles.
Andrea Gregorio Gomes, Lea Broche, Bruno Payre, Emile Perez, Celine Picard, Sophie Franceschi   +5 more
wiley   +1 more source

Initial Pre‐Clinical Evaluation of the Augmented Ultra‐Low Temperature Cryoablation Catheter for Ventricular Ablations

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction Ultra‐low Temperature Cryoablation (ULTC) using nitrogen cryogen near its boiling temperature of −196°C is a novel cardiac ablation modality capable of producing titratable lesions with depth exceeding 10 mm and has been recently introduced for catheter treatment of drug‐refractory ventricular tachycardia (VT). The ablative action
Katia Dyrda, Atul Verma, Borislav Dinov, Thomas Fink, Tom De Potter, Santi Raffa, Martin Sirois, Marie‐Elaine Clavet‐Lanthier, Ilya Grigorov, Pedram Pourfard, Alex Babkin, Vidal Essebag   +11 more
wiley   +1 more source

Precise Geoid Determination in the Eastern Swiss Alps Using Geodetic Astronomy and GNSS/Leveling Methods. [PDF]

Sensors (Basel)
Albayrak M, Marti U, Willi D, Guillaume S, Hardy RA.   +4 more
europepmc   +1 more source

Fish welfare in a changing world: New developments and current challenges

Journal of Fish Biology, EarlyView.
Abstract The welfare of non‐human animals is central to ethical discussions on animal use, with increasing attention to fish welfare across research, aquaria, aquaculture, and fisheries. This paper reviews current theoretical approaches to animal welfare and recent advances in defining and assessing fish welfare since the seminal paper by Huntingford ...
Sonia Rey Planellas, João L. Saraiva, Eliane Gonçalves‐de‐Freitas, Pablo Arechavala‐Lopez, Bernice Bovenkerk, Michael Breen, Steven J. Cooke, Martin Føre, Lene Northwood, Lars Helge Stien, Sunil Kadri, Chris Noble, Jonatan Nilsson, Fernando Rodriguez, Cosme Salas, Peter Sandøe, Hans van de Vis   +16 more
wiley   +1 more source