Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
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Identification and rescue of congenital hyperinsulinism-associated ABCC8 mutations that impair K<sub>ATP</sub> channel trafficking. [PDF]
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Voltage-dependent G-protein regulation of Ca<sub>V</sub>2.2 (N-type) channels. [PDF]
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A Single Dose of a Psychedelic Drug Repairs Prefrontal Cortex Synaptic Physiology in a Mouse Model of Prenatal Alcohol Exposure. [PDF]
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Steady-state rectilinear motion of a load on an ice sheet modeled by a viscoelastic plate is considered. The viscoelastic properties of ice are described using the linear Maxwell and Kelvin-Voigt models and a generalized Maxwell-Kelvin model. Calculated vertical displacements and strains of the ice plate are compared with available experimental data.
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Mathematical modelling of ice beam deflection dynamics
2021The assessment of stresses arising from the interaction of the ice field and inclined structures is an important part of research in ice mechanics. For these purposes, various mathematical tools are used, including mechanical models of beams. The article presents solutions for the equation of dynamic deflection of a beam with different boundary ...
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Buckling and Deflection of Ice Sheet Caused by Ship
The Journal of Ocean, Mechanical and Aerospace -science and engineering- (JOMAse), 2018The movement of ice ship gradually gives load to the ice sheet, along with that, the ice sheet will react in proportion to the load of the ship. The phenomenon of interaction between ice and hull of ship has been studied by researchers through empirical mathematical simulation and experiment. This paper discusses the phenomena of ice sheet buckling and
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