Results 71 to 80 of about 663,567 (291)

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Microbiology: lessons from a first attempt at Lake Ellsworth [PDF]

, 2015
During the attempt to directly access, measure and sample Subglacial Lake Ellsworth in 2012–2013, we conducted microbiological analyses of the drilling equipment, scientific instrumentation, field camp and natural surroundings.
Holt, G., Woodward, J., Pearce, D. A., Tranter, Martyn, Mowlem, M., Siegert, Martin J, Siegert, M.J., Siegert, M. J., Magiopoulos, I., Pearce, D.A., Tranter, M., Woodward, J, Woodward, John, Holt, Giles, Magiopoulos, Iordanis, Mowlem, Matt, Pearce, David, Siegert, Martin   +17 more
core   +3 more sources

A new portable ice-core drilling machine: application to tephra studies

, 1998
A new portable device for ice-core drilling, specially designed for thin tephra-layer sampling, was tested on the South Shetland glaciers during the 1994-95 Antarctic summer.
F. Sàbat, J. M. Vilaplana, D. M. Pomeroy, J. M. Casas, J. M. Parés   +4 more
core   +2 more sources

Theoretical and experimental study on cutting temperature in the presence of drilling fluid during ice-core drilling

Journal of Glaciology
Warm ice at temperatures close to the pressure melting point is often encountered in deep ice-core drilling. The heat generated by rotary cutting can melt ice chips, which seriously threatens the safety of drilling if the chips refreeze on the drill bit ...
Zhuo Chen, Pinlu Cao, Han Wang, He Yang, Qilei Yin   +4 more
doaj   +1 more source

Recent Advances in Carbon Cathode Materials toward High‐Performing Zinc‐Ion Hybrid Supercapacitors

Advanced Science, EarlyView.
Aqueous zinc‐ion hybrid supercapacitors (ZHSCs) have emerged as promising next‐generation electrochemical energy‐storage devices. Porous carbon materials have been extensively studied as cathodes, with advances in tailoring pore structures and material properties to enhance performance.
Take Hirooka, Zhaolin Liu, Ivan P. Parkin, Guanjie He   +3 more
wiley   +1 more source

Deep Drilling with the ANDRILL Program in Antarctica [PDF]

Scientific Drilling, 2006
ANDRILL (ANtarctic geological DRILLing) is a new international, multi-disciplinary drilling program that targets geological records that lie hidden beneath the icy blanket of Antarctica. The primary objective is to investigate Antarctica’s role in global
Alex Pyne, Ross Powell, Tim Naish, Fabio Florindo, Jim Cowie, David Harwood, Richard Levy   +6 more
doaj   +1 more source

Performance Estimation and Ex Vivo Validation of Untethered Magnetic Robots in Soft Tissue

Advanced Science, EarlyView.
This study presents an empirical model that quantitatively predicts the step‐out frequency of screw‐type untethered magnetic robots (UMRs) in soft viscoelastic environments, including ex vivo brain tissue. By integrating key parameters into a dimensionless framework, the model enables estimation of robot performance across a range of biological ...
Leendert‐Jan W. Ligtenberg, Thijs J. van der Burg, Stijn Y. Kolkman, Santiago Saavedra Castano, David Fernandez Rivas, Anke Klingner, Roger M. L. M. Lomme, Lucas S. Joziasse, Dorothee Wasserberg, H. Remco Liefers, Doron Ben Ami, Udi Sadeh, Oded Shoseyov, Giulio Dagnino, Pascal Jonkheijm, Jurgen J. Fütterer, Stefano Stramigioli, J. Frank W. Nijsen, Michiel C. Warlé, Islam S. M. Khalil   +19 more
wiley   +1 more source

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

Drilling Performance Evaluation and Mechanism Analysis of Diamond-Coated Drills in Ice-Supported CFRP Machining

Journal of Manufacturing and Materials Processing
Diamond-coated tools are suitable for CFRP machining because of their high hardness, sharp cutting edge, and good wear resistance. However, the anisotropic and heterogeneous nature of CFRP makes drilling-induced defects, such as burrs, tearing, fiber ...
Bohan Yuan, Yixin Jin, Ming Jin, Wenjie Zhang, Bin Wan, Huaxing Yang, Zhao Zhang   +6 more
doaj   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source