Results 71 to 80 of about 645,925 (247)

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Effects of convex surface roughness on heterogeneous ice nucleation

AIP Advances
In this work, we investigate the effects of convex surface roughness on heterogeneous ice nucleation through molecular dynamics simulations. Graphene surfaces with sawtooth structures are considered, and the ice nucleation rates are calculated by varying
Yixiang Wang, Jingwen Mo, Shuang Luo, Yu Zhang, Baoling Huang, Zhigang Li   +5 more
doaj   +1 more source

Predicting heterogeneous ice nucleation with a data-driven approach

Nature Communications, 2020
Heterogenous ice nucleation is a ubiquitous phenomenon, but predicting the ice nucleation ability of a substrate is challenging. Here the authors develop a machine-learning data-driven approach to predict the ice nucleation ability of substrates, which ...
Martin Fitzner, Philipp Pedevilla, Angelos Michaelides   +2 more
doaj   +1 more source

Sensitivity studies of dust ice nuclei effect on cirrus clouds with the Community Atmosphere Model CAM5 [PDF]

Atmospheric Chemistry and Physics, 2012
In this study the effect of dust aerosol on upper tropospheric cirrus clouds through heterogeneous ice nucleation is investigated in the Community Atmospheric Model version 5 (CAM5) with two ice nucleation parameterizations.
X. Liu, X. Shi, K. Zhang, E. J. Jensen, A. Gettelman, D. Barahona, A. Nenes, P. Lawson   +7 more
doaj   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths

Advanced Science, EarlyView.
At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel, Soumik Ray, Federica Saraceno, Giacomo Nisini, Georgia Nasi, Thomas Oliver Mason, Antonin Kunka, Effrosyni Agrimaki, Dannie Juul Olesen, Francesco Simone Ruggeri, Alexander K. Buell   +10 more
wiley   +1 more source

Analysis of the effect of water activity on ice formation using a new thermodynamic framework [PDF]

Atmospheric Chemistry and Physics, 2014
In this work a new thermodynamic framework is developed and used to investigate the effect of water activity on the formation of ice within supercooled droplets.
D. Barahona
doaj   +1 more source

Neutron diffraction and NMR relaxation studies of structural variation and phase transformations for water/ice in SBA-15 silica: I. The over-filled case [PDF]

, 2006
Neutron diffraction and NMR relaxation measurements have been made of water/ice in SBA-15, a mesoporous silica constituting an ordered array of cylindrical mesopores of pore diameter similar to 86 angstrom, over the temperature range 180-300 K in a ...
Webber, J. Beau W., G H Findenegg, Khushalani, S., Findenegg, G.H., E Liu, T Hansen, Hansen, Thomas, J C Dore, Dore, J. C., Hansen, T., D Khushalani, Khushalani, D., Jähnert, S., J B W Webber, Findenegg, G. H., Webber, Beau, S Jähnert, Liu, E., Dore, John C.   +18 more
core   +1 more source

Atmospheric Water Harvesting Through Polymer Hydrogel Sorbents: Materials Chemistry, Design Strategies, and Applications

Advanced Science, EarlyView.
Polymer‐based hydrogels have emerged as promising materials for atmospheric water harvesting (AWH) due to their high water affinity, tunable network structure, and excellent moisture adsorption‐desorption performance. Functional hydrogel systems enable efficient water capture and controlled release under low‐energy conditions, offering a sustainable ...
Swagata Datta, Sushmit Sen, Nilanjan Dey, Amrita Chatterjee, Ananya Sadhu, Sudipta Sarkar, Pradip K. Maji   +6 more
wiley   +1 more source

Oxalic acid as a heterogeneous ice nucleus in the upper troposphere and its indirect aerosol effect [PDF]

, 2006
Zobrist B, Marcolli C, Koop T, et al. Oxalic acid as a heterogeneous ice nucleus in the upper troposphere and its indirect aerosol effect. ATMOSPHERIC CHEMISTRY AND PHYSICS.
Koop, Thomas, Cziczo, Daniel J., Corti, Thierry, Murphy, D. M., Fueglistaler, Stephan, B. Zobrist, P. K. Hudson, Koop, T., Hudson, P.K., Koop, Thomas ; https://orcid.org/, Krieger, U. K., Corti, T., Lohmann, Ulrike, Thomson, D. S., U. K. Krieger, Marcolli, C., D. S. Thomson, D. J. Cziczo, T. Corti, T. Peter, U. Lohmann, Lohmann, U., Peter, Thomas, T. Koop, Luo, Beiping P., Murphy, Daniel M., A. A. Zardini, Krieger, Ulrich; id_orcid, Luo, B. P., Hudson, P. K., Thomson, D.S., B. P. Luo, Zardini, A., Cziczo, D. J., Zardini, A. A., Zardini, Alessandro A., D. M. Murphy, C. Marcolli, S. Fueglistaler, Peter, T., Marcolli, Claudia, Zobrist, Bernhard, Zobrist, B., Fueglistaler, S.   +43 more
core   +2 more sources