Results 41 to 50 of about 360,583 (246)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Motion of a submerged body in a near-surface water environment

International Journal of Naval Architecture and Ocean Engineering, 2022
This study considered the motion of a submerged body near the free surface of a liquid and a liquid covered with ice cover, both theoretically and experimentally. Mathematically, the body was modelled using the source–sink system.
Vitaly Zemlyak, Alexandra Pogorelova, Victor Kozin   +2 more
doaj   +1 more source

CRACK FORMATION IN ICE PLATES BY THERMAL SHOCK

Canadian Journal of Physics, 1963
Cracks were formed in the surface of smooth ice blocks by bringing them into contact with a second colder ice block. The temperature change within each block and the associated thermal stress were calculated. The ultimate strength of a smooth ice surface was found to be between 30 and 40 kg/cm2.
openaire   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Experiment Investigation on Distribution of Ice Crystal During Initial Period of Frost Growth

Zhileng xuebao, 2006
With the picture magnifying and collecting system,ice crystal shape was observed and the picture of ice crystal at different circumstance was obtained.Then the digital image processing method was used to convert the initial picture into binary image.On ...
侯普秀, 蔡亮, 虞维平
doaj   +2 more sources

Numerical and Experimental Investigation of the Design of a Piezoelectric De-Icing System for Small Rotorcraft Part 3/3: Numerical Model and Experimental Validation of Vibration-Based De-Icing of a Flat Plate Structure

Aerospace, 2020
The objective of this research project is divided in four parts: (1) to design a piezoelectric actuator-based de-icing system integrated to a flat plate experimental setup and develop a numerical model of the system with experimental validation, (2) use ...
Eric Villeneuve, Christophe Volat, Sebastian Ghinet   +2 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Evaluation of Retrieval Algorithms for Ice Microphysics Using CALIPSO/CloudSat and Earthcare

EPJ Web of Conferences, 2016
We developed lidar-radar algorithms that can be applied to Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation (CALIPSO) lidar and CloudSat data to retrieve ice microphysics.
Okamoto Hajime, Sato Kaori, Hagihara Yuichiro, Ishimoto Hiroshi, Borovoi Anatoli, Konoshonkin Alexander, Kustova Natalia   +6 more
doaj   +1 more source

Two independent methods for mapping the grounding line of an outlet glacier – an example from the Astrolabe Glacier, Terre Adélie, Antarctica [PDF]

The Cryosphere, 2014
The grounding line is a key element of coastal outlet glaciers, acting on their dynamics. Accurately knowing its position is fundamental for both modelling the glacier dynamics and establishing a benchmark for later change detection.
E. Le Meur, M. Sacchettini, S. Garambois, E. Berthier, A. S. Drouet, G. Durand, D. Young, J. S. Greenbaum, J. W. Holt, D. D. Blankenship, E. Rignot, J. Mouginot, Y. Gim, D. Kirchner, B. de Fleurian, O. Gagliardini, F. Gillet-Chaulet   +16 more
doaj   +1 more source