Results 51 to 60 of about 787,199 (292)

Dynamic Wind-Tunnel Testing of a Sub-Scale Iced S-3B Viking [PDF]

open access: yes
The effect of ice accretion on a 1/12-scale complete aircraft model of S-3B Viking was studied in a rotary-balance wind tunnel. Two types of ice accretions were considered: ice protection system failure shape and runback shapes that form downstream of ...
Barnhart, Billy   +2 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

National and European Critical Infrastructure

open access: yesApplied Medical Informatics, 2021
What exactly is the national critical infrastructure? According to the law, we identify several conditions that must be met in terms of the vocation of an element, system or component thereof to be identified as a potential national critical ...
Călin MUNTEAN   +2 more
doaj  

RECOVERING THE VERTICAL CLOUD PROFILE USING ACTIVE-PASSIVE SENSING [PDF]

open access: yesРадиофизика и электроника, 2017
The research regarding the liquid water content of clouds is quite important for the study of physical processes in the atmosphere, and development of ice protection system. The paper analyzes the possibilities of using the active-passive sounding method
A. B. Veselovskaya   +6 more
doaj   +1 more source

Electromechanical Resonant Ice Protection Systems: Analysis of Fracture Propagation Mechanisms [PDF]

open access: yesAIAA Journal, 2018
Recent research is showing growing interest in low-power electromechanical de-icing systems and, in particular, de-icing systems based on piezoelectric actuators. These systems use the vibrations generated by piezoelectric actuators at resonance frequencies to produce shear stress at the interface between the ice and the support or to produce tensile ...
Budinger, Marc   +5 more
openaire   +3 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Icing tunnel tests of a glycol-exuding porous leading edge ice protection system on a general aviation airfoil [PDF]

open access: yes
A glycol-exuding porous leading edge ice protection system was tested. Results show that the system is very effective in preventing ice accretion (anti-ice mode) or removing ice from an airfoil.
Albright, A. E.   +3 more
core   +1 more source

Ultrasonic ice protection systems

open access: yes, 2017
Protection systems against ice on leading edge conventionally use thermal and pneumatic solutions. In case of thermal solutions with piccolo tubes (the most usual technology), the hot air is extracted from engine, which decrease its efficiency. The trend is to move to all electric deicing systems.
Rouset, Pierrick   +2 more
openaire   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Reconstruction of St. Petersburg roofs based on light steel thin-walled structures and de-icing system [PDF]

open access: yesИнженерно-строительный журнал, 2010
Insecurity of applied coatings and low service lives of St. Petersburg roofs generate the development of new technological solutions. Necessity of roof protection from the ice dams is a special factor in selecting technological solutions of the roof ...
N.I. Vatin   +4 more
doaj  

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