Results 61 to 70 of about 316,907 (302)

A Common Origin for Ridge-and-Trough Terrain on Icy Satellites by Sluggish Lid Convection [PDF]

open access: yes, 2015
Ridge-and-trough terrain is a common landform on outer Solar System icy satellites. Examples include Ganymede's grooved terrain, Europa's gray bands, Miranda's coronae, and several terrains on Enceladus.
Barr, Amy C., Hammond, Noah P.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Evolution of the structure of amorphous ice - from low-density amorphous (LDA) through high-density amorphous (HDA) to very high-density amorphous (VHDA) ice

open access: yes, 2005
We report results of molecular dynamics simulations of amorphous ice for pressures up to 22.5 kbar. The high-density amorphous ice (HDA) as prepared by pressure-induced amorphization of Ih ice at T=80 K is annealed to T=170 K at various pressures to ...
D. Donadio   +3 more
core   +1 more source

Ice decay and the ice regime system

open access: yes, 2001
The Canadian Ice Regime System takes into account the decay of sea ice by allowing the addition of +1 to the Ice Multiplier for ice that is deemed to be decayed at the "rotten" stage. This report examines this approach based on an analysis of the strength of both first-year sea ice and multi-year sea ice, and the damage statistics for Arctic vessels ...
Timco, G. W., Johnston, M., Kubat, I.
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Weather Atlas for Hydrographic Work in the Arctic on the Example of the Barents Sea

open access: yesРоссийская Арктика, 2022
Based on the results of research and literature data, the methodology of compiling the manual "Weather Atlas for hydrographic work in the Arctic" is considered.
Sharonov Andrey Yurievich, Shmatkov V.A.
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Regime-dependence when constraining a sea ice model with observations: lessons from a single-column perspective [PDF]

open access: yesThe Cryosphere
A substantial body of work has explored the use of sea ice concentration (SIC) and sea ice thickness (SIT) observations to initialize modeled estimates of the unobserved Arctic sea ice state via data assimilation (DA).
M. M. Wieringa   +2 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Effect of climate change on thermal-ice regime of shallow lakes compared to deep lakes: Case study of lakes in the temperate zone (Northern Poland)

open access: yesJournal of Limnology, 2018
The objective of this study is to determine the usefulness of results of hydrological observations (1961-2015) carried out in a deep lake for the assessment changes in the ice-thermal regime of a shallow lake.
Włodzimierz Marszelewski, Bożena Pius
doaj   +1 more source

Home - About - Disclaimer - Privacy