Results 161 to 170 of about 72,753 (311)

Field determination of the densities of lake ice sheets [PDF]

, 1976
William P. Adams
openalex   +1 more source

Cancer Immunotherapy via Disruption of Integrin αvβ3 and CD47 Costabilization on Cancer Cell Surface

Advanced Science, EarlyView.
This study identifies a cancer‐specific interaction between CD47 and integrin αvβ3 that facilitates immune evasion. A rationally designed peptide, PSFL‐NK13, disrupts this axis, enhancing macrophage‐mediated phagocytosis and suppressing tumor growth without inducing anemia.
Peng‐Cheng Yu, Chen‐Xi Yue, Wen‐Zhong Dong, Cui‐Yun Hao, Yi‐Fan Qiao, Di Liu, Xin Zhang, Qi Zhan, Jia‐Bao Yao, Dong‐Ping Wang, Peng Cao, Ying‐Zhe Fan, Ye Yu   +12 more
wiley   +1 more source

The encoded and expressed biosynthetic potential of Greenland Ice Sheet microbes. [PDF]

Front Microbiol
Jaarsma AH, Sipes K, Zervas A, Feord HK, Campuzano Jiménez F, Thøgersen MS, Benning LG, Tranter M, Anesio AM.   +8 more
europepmc   +1 more source

Millennial-scale variability of the Antarctic ice sheet during the early Miocene. [PDF]

Proc Natl Acad Sci U S A, 2023
Sullivan NB, Meyers SR, Levy RH, McKay RM, Golledge NR, Cortese G.   +5 more
europepmc   +1 more source

Antarctic Ice-Sheet Volume at 18000 Years B.P. and Holocene Sea-Level Changes at the West Antarctic Margin [PDF]

, 1979
Craig S. Lingle, J. A. Clark
openalex   +1 more source

Hepatitis E Virus ORF1 Polyprotein Harbors a Pocket‐Like Cavity That Is Vital for Virus Replication and Represents a Novel Antiviral Target

Advanced Science, EarlyView.
Within the hepatitis E virus (HEV) ORF1 polyprotein, the X domain interacts with viral RNA‐dependent RNA polymerase (RdRp), forming a functional “pocket‐like” cavity (PC) that is crucial for viral replication. Structure‐based screening, surface plasmon resonance (SPR) assays, and HEV model validation collectively identify saikosaponin D and ...
Xiaohui Ding, Dou Zeng, Dan Liu, Yingying Bian, Bin Li, Zheng Li, Qiudi Li, Shiquan Liang, Yunlong Si, Qili Yao, Yibo Ding, Jiahui Zhu, Xiangyang Li, Kuiyang Zheng, Hongbo Guo, Wenshi Wang   +15 more
wiley   +1 more source

Meltwater ponding has an underestimated radiative effect on the surface of the Greenland Ice Sheet. [PDF]

Nat Commun
Ryan JC, Cooper MG, Cooley SW, Rennermalm ÅK, Smith LC.   +4 more
europepmc   +1 more source

Methylotrophic Communities Associated with a Greenland Ice Sheet Methane Release Hotspot. [PDF]

Microb Ecol, 2023
Znamínko M, Falteisek L, Vrbická K, Klímová P, Christiansen JR, Jørgensen CJ, Stibal M.   +6 more
europepmc   +1 more source

The Dependence of Temperature Profiles in Ice Sheets on Longitudinal Variations in Velocity and Surface Temperature [PDF]

, 1978
Alex S Jones
openalex   +1 more source

TBC1D22B Regulates ER‐to‐Golgi Trafficking via RAB1B Inactivation and Promotes Oncogenic Programs in Breast Cancer

Advanced Science, EarlyView.
TBC1D22B, a Golgi‐localized RabGAP linked to poor prognosis in breast cancer, inhibits ER‐to‐Golgi transport via RAB1B inactivation. This disrupts secretion, drives oncogenic transcriptional reprogramming, and promotes tumor growth. These findings indicate that TBC1D22B connects membrane trafficking to transcriptional control and cancer progression ...
Flavia Martino, Mariadomenica Lupi, Alessandra Murabito, Fabio Bedin, Giulia Villari, Linda Andreoli, Stefano Freddi, Bronislava Matoskova, Rosa Pennisi, Stella Fontana, Amir Fardin, Gaelle Boncompain, Franck Perez, Federico Bussolino, Alessandro Cuomo, Sara Sigismund, Letizia Lanzetti   +16 more
wiley   +1 more source