Results 51 to 60 of about 72,753 (311)

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

On the dynamics of the ice sheets 2

Journal of Geophysical Research: Oceans, 1981
The equation which describes the motion of an ice sheet under its own weight has a cylindrically symmetric similarity solution. The initial value problem of the equation of motion which has been linearized in the deviations from this similarity solution is solved by an expansion of the solution in terms of eigenfunctions of the linearized equation. The
openaire   +4 more sources

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

EXTRACTION OF ICE SHEET LAYERS FROM TWO INTERSECTED RADAR ECHOGRAMS NEAR NEEM ICE CORE IN GREENLAND [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2016
Accumulation of snow and ice over time result in ice sheet layers. These can be remotely sensed where there is a contrast in electromagnetic properties, which reflect variations of the ice density, acidity and fabric orientation. Internal ice layers are
S. Xiong, J.-P. Muller
doaj   +1 more source

Bioinspired Materials, Designs, and Manufacturing Strategies for Advanced Impact‐Resistant Helmets

Advanced Engineering Materials, EarlyView.
This review explores how bioinspired materials, structures, and manufacturing strategies transform helmet design to achieve enhanced impact resistance. Drawing inspiration from nacre, porcupine quills, beetle exoskeletons, and skull architectures, it highlights advances in auxetic lattices, nanocomposites, and functionally graded foams.
Joseph Schlager, Yi Jin, Mohammad Faruk, Jay Alberts, C. Chase Cao   +4 more
wiley   +1 more source

A rapidly converging initialisation method to simulate the present-day Greenland ice sheet using the GRISLI ice sheet model (version 1.3) [PDF]

Geoscientific Model Development, 2019
Providing reliable projections of the ice sheet contribution to future sea-level rise has become one of the main challenges of the ice sheet modelling community.
S. Le clec'h, S. Le clec'h, A. Quiquet, A. Quiquet, S. Charbit, C. Dumas, M. Kageyama, C. Ritz   +7 more
doaj   +1 more source

Development of SiC Nanocomposites Using Direct Ink Writing Process

Advanced Engineering Materials, EarlyView.
Herein, feedstock inks containing polycarbosilane and various concentrations of SiC nanoparticles (SiCnp) are investigated for fabricating ceramic matrix composites using a DIW 3D printing process. Characterization results from physical measurement, microstructure analysis, and thermal and flexural testing suggested that high‐performance CMC samples ...
Jinchen Han, Israa Eltahir Ali Elfaki, Luke Weston, Chenggang Chen, Donald A. Klosterman, Li Cao   +5 more
wiley   +1 more source

Investigating the local-scale influence of sea ice on Greenland surface melt [PDF]

The Cryosphere, 2017
Rapid decline in Arctic sea ice cover in the 21st century may have wide-reaching effects on the Arctic climate system, including the Greenland ice sheet mass balance. Here, we investigate whether local changes in sea ice around the Greenland ice sheet
J. C. Stroeve, J. C. Stroeve, J. R. Mioduszewski, A. Rennermalm, L. N. Boisvert, M. Tedesco, D. Robinson   +6 more
doaj   +1 more source

Transforming Cellulose Into Functional Three‐Dimensional Structures

Advanced Functional Materials, EarlyView.
Cellulose is promising for replacing synthetic polymers due to its excellent mechanical properties and low cost. This review highlights the recent advancements in transforming cellulose into functional 3D structures, including liquid gels and porous materials.
Xia Sun, Hao Sun, Penghui Zhu, Yonggang Wu, Anna Palmer, Feng Jiang   +5 more
wiley   +1 more source

Modelling the Early Weichselian Eurasian Ice Sheets: role of ice shelves and influence of ice-dammed lakes [PDF]

Climate of the Past, 2007
During the last glaciation, a marine ice sheet repeatedly appeared in Eurasia. The floating part of this ice sheet was essential to its rapid extension over the seas.
V. Peyaud, C. Ritz, G. Krinner
doaj