Results 81 to 90 of about 532,419 (357)

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

Last deglaciation of northern continental Europe

Cuadernos de Investigación Geográfica, 2015
Correlation of main ice sheet limits in northern continental Europe during Late Weichselian is presented, based on available data concerning occurrence of ice-marginal formations and their radiometric dating.
L. Marks
doaj   +1 more source

Calibrating an ice sheet model using high-dimensional binary spatial data

, 2016
Rapid retreat of ice in the Amundsen Sea sector of West Antarctica may cause drastic sea level rise, posing significant risks to populations in low-lying coastal regions.
Applegate, Patrick, Chang, Won, Haran, Murali, Pollard, David   +3 more
core   +2 more sources

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

GRANTSISM: An Excel™ ice sheet model for use in introductory Earth science courses [PDF]

, 2018
GRANTISM (GReenland and ANTarctic Ice Sheet Model) is an educational Excel™ model introduced by Pattyn (2006). Here, GRANTISM is amended to simulate the Svalbard-Barents-Sea Ice Sheet during the Last Glacial Maximum, an analogue for the contemporary West
Gowan, Evan J., Ingólfsson, Ólafur, Jakobsson, Martin, Kirchner, Nina, Noormets, Riko, Pattyn, Frank, van Dongen, Eef   +6 more
core   +2 more sources

Physicochemical Reinforcement Unlocks Sterilization‐Stable Anisotropic Hydrogels for Cell‐Compatible Mock Arteries

Advanced Healthcare Materials, EarlyView.
ABSTRACT In vitro arterial models offer ethical and robust alternatives for vascular research but require cytocompatible materials that replicate physiological mechanics. Poly(vinyl alcohol) (PVA) hydrogels produced by directional freezing and salting‐out (PVA DFSO) are anisotropic yet lack stability for cell culture. Herein, methacrylated PVA (PVA‐MA)
Javiera Sanhueza Ortega, Kirthen Shanmuganathan, Laura Poole‐Warren, Susann Beier, Ulises Aregueta Robles   +4 more
wiley   +1 more source

Core handling and processing for the WAIS Divide ice-core project [PDF]

, 2017
On 1 December 2011 the West Antarctic Ice Sheet (WAIS) Divide ice-core project reached its final depth of 3405 m. The WAIS Divide ice core is not only the longest US ice core to date, but is also the highest-quality deep ice core, including ice from the ...
Bencivengo, Brian M., Cravens, Eric D., Hargreaves, Geoffrey M., Johnson, Jay A., Kippenhan, Matthew J., Neff, Peter D., Nunn, Richard M., Orsi, Anais J., Popp, Trevor J., Rhoades, John F., Souney, Joseph M., Taylor, Kendrick C., Twickler, Mark S., Vaughn, Bruce H., Voigt, Donald E., Wong, Gifford J.   +15 more
core   +1 more source

A temperate former West Antarctic ice sheet suggested by an extensive zone of bed channels [PDF]

, 2014
Several recent studies predict that the West Antarctic Ice Sheet will become increasingly unstable under warmer conditions. Insights on such change can be assisted through investigations of the subglacial landscape, which contains imprints of former ice ...
Anne M. Le Brocq, Bamber, Bartholomew, Bartholomew, Cook, Cowton, David M. Rippin, DeConto, Dowsett, Fausto Ferraccioli, Fowler, Fretwell, Haran, Hugh F.J. Corr, Jordan, Joughin, Kathryn C. Rose, Le Brocq, Lewis, Martin J. Siegert, Miller, Mote, Naish, Neil Ross, Nitsche, Pritchard, Raymo, Rignot, Robert G. Bingham, Ross, Ross, Schoof, Shepherd, Smith, Sugden, Tom A. Jordan, Trusel, Wingham, Wright, Wright, Young, Zachos   +41 more
core   +2 more sources

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

Advanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee, Seongchan Kim, Jooyeun Chong, Min‐gyeong Kim, Kayeong Lim, Nan‐Ee Lee, Jahyun Koo, Jiheong Kang, Hyojin Lee   +8 more
wiley   +1 more source

A stochastic parameterization of ice sheet surface mass balance for the Stochastic Ice-Sheet and Sea-Level System Model (StISSM v1.0) [PDF]

Geoscientific Model Development
Many scientific and societal questions that draw on ice sheet modeling necessitate sampling a wide range of potential climatic changes and realizations of internal climate variability.
L. Ultee, L. Ultee, A. A. Robel, S. Castruccio   +3 more
doaj   +1 more source