Results 81 to 90 of about 630,227 (329)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Basal terraces on melting ice shelves [PDF]

open access: yes, 2014
Ocean waters melt the margins of Antarctic and Greenland glaciers, and individual glaciers' responses and the integrity of their ice shelves are expected to depend on the spatial distribution of melt.
Corr, Hugh F J.   +6 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Southern Ocean warming: Increase in basal melting and grounded ice loss [PDF]

open access: yes, 2013
We apply a global finite element sea ice/ice shelf/ocean model (FESOM) to the Antarctic marginal seas to analyze projections of ice shelf basal melting in a warmer climate.
Determann, Jürgen   +2 more
core  

The role of ocean cooling in setting glacial southern source bottom water salinity [PDF]

open access: yes, 2012
At the Last Glacial Maximum (LGM), the salinity contrast between northern source deep water and southern source bottom water was reversed with respect to the contrast today.
Adkins, J. F.   +3 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Modeling Antarctic tides in response to ice shelf thinning and retreat [PDF]

open access: yes, 2014
Tides play an important role in ice sheet dynamics by modulating ice stream velocity, fracturing, and moving ice shelves and mixing water beneath them.
Green, J. A. M.   +3 more
core   +6 more sources

Instantaneous Antarctic ice sheet mass loss driven by thinning ice shelves

open access: yesGeophysical Research Letters, 2019
Recent observations show that the rate at which the Antarctic ice sheet (AIS) is contributing to sea level rise is increasing. Increases in ice‐ocean heat exchange have the potential to induce substantial mass loss through the melting of its ice shelves.
G. Gudmundsson   +3 more
semanticscholar   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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